Don Pepe was my most favourite stay throughout my South America trip. Although the room was small in size, you'll managed. Stayed for 3 nites and the room was toasty till we had to leave the balcony door ajar. The bathroom even had a heater. So you'll be warm anywhere in the room. Wi-fi was patchy though, with the signal dropping at some points in the room. Breakfast (Bread, ham, cheese, juice, coffee/tea, yogurt and assortment of pastries) was simple but filling. Alejandro and Andrea, the owners, were perfect hosts. They made you feel very welcome and made sure we were well taken care of. We had booked a Perito Moreno Glacier tour and the pick up was delayed and without asking, Alejandro made a call to the agent to check on our behalf. I really appreciated this kind act and the many other gestures shown during our stay. Location was slightly off the center of town but still walkable (under 5 - 10 mins). El Calafate is a small town anyway. Airport transfers can be easily arranged with an email. I also hope they can place a small towel mat in the bathroom, as after a shower the flooring can get really wet.
What a wonderful stay and more importantly, what wonderful hosts! Highly recommended!