This is a great place to stay.
We booked a suite on the upper floor as part of our honeymoon. It was fantastic. Spotlessly clean, great view (see photos) and loads of space.
The hotel's location is great. It's walking distance to the Plaza de Armas (10 minutes) and Bella Vista neighbourhood.
The food at breakfast was good without being stunning but there is plenty of it and the staff are so friendly and helpful. We had to leave for a morning flight before breakfast opened but they made us a packed lunch to take with us which was very generous. There is a little snack station by the backdoor with tea, coffee, biscuits and fruit.
The rooftop pool is good to cool off but don't expect to swim any laps. It's got a great view. We took our drinks up there in the afternoon and had the place to ourselves.
The staff at the hotel were great. They helped us book transport, arrange treats for my wife in our room upon arrival (special mention for Gustavo) and with directions to ensure we didn't go protest areas during our time in Santiago.
I would definitely recommend staying at Hotel Ismael if you are in Santiago.