Hotel>Missouri>Saint Louis>21C Museum Hotel St Louis

Bedroom 1, 21C Museum Hotel St Louis, Saint Louis

Exterior & Views, 21C Museum Hotel St Louis, Saint Louis

Sport & Beauty 3, 21C Museum Hotel St Louis, Saint Louis

Public Area 4, 21C Museum Hotel St Louis, Saint Louis

Bedroom 5, 21C Museum Hotel St Louis, Saint Louis

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General Info

Reviews

Location

Accommodation Policy

About

Hotel

21C Museum Hotel St Louis

Q: What is the address of 21C Museum Hotel St Louis?

21C Museum Hotel St Louis is located at 1528 Locust street, St. Louis, Missouri, US

Q: What are the standard check-in & check-out times of 21C Museum Hotel St Louis?

The standard check-in time at 21C Museum Hotel St Louis is starting from 4:00 PM-11:00 AM and the latest check-out time is at 11:00 am

Q: What are the facilities available in 21C Museum Hotel St Louis?

Facilities available in the hotel are (some may require extra charges): WiFi, Fitness Center, tiket Green, Spa, 24-hour Front Desk

4.4/5

(106 reviews)

Saint Louis, Missouri

Start from

USD 239

/room/night

The Fun Awaits

Perfect for nature loversOnly 384 m to Citygarden and 2 km to Jefferson National Expansion Memorial Park

Tourist attractions nearbyOnly 372 m to St. Louis Children's Aquarium/World Aquarium

Comfy place to relax and rechargePamper yourself with sport, spa, and recreation.

Near shopping centersOnly 2 km to Laclede's Landing and 3 km to Soulard Farmer's Market

Nice location! Near public transportOnly 1 km to St. Louis Gateway Station and 1.2 km to 8th and Pine Station

Suitable for your business tripStay productive with business facilities.

Reviews

See all

4.4/5

GoodFrom 106 reviews

5.0/515 Jan 2025

Michael • Family Trip

Cool spot

5.0/515 Jan 2025

Kevin • Couple Trip

A Perfectly Curated Wes Anderson-Style Stay at 21c Museum Hotel St. Louis The 21c Museum Hotel in St. Louis is nothing short of extraordinary—a perfectly curated Wes Anderson-esque experience that feels as if you’ve stepped into a cinematic dream. From the moment we arrived, we were immersed in the hotel’s vibrant yet sophisticated aesthetic, seamlessly blending artistry and luxury. Our corner suite was a highlight, featuring impeccable design and one of the most stunning bathrooms we’ve ever seen. Every detail, from the decor to the amenities, exuded thoughtful elegance. The spacious layout and expansive views made it a true haven of relaxation. The hotel’s dedication to merging art and hospitality sets it apart. Wandering through the gallery-like spaces was a delightful experience, with each piece adding to the hotel’s unique charm. The staff was attentive and welcoming, ensuring our stay was flawless from start to finish. This was, without a doubt, one of the finest hotels we’ve ever stayed at. We are eagerly anticipating our return, this time to indulge in the duplex 21c Suite, which promises an even more extraordinary stay. For anyone seeking an unforgettable blend of art, design, and luxury, the 21c Museum Hotel St. Louis is an absolute must-visit.

5.0/513 Jan 2025

John • Couple Trip

How friendly the velet parking people were. Didnt really car for it being a lane pool and how expiedia stated the rooms were sound proof when they were not. But other than that it was an amazing stay!

5.0/512 Jan 2025

Becky

10 out of 10. This will be our new STL staycation when we need a night away. Restaurant was fabulous - food drinks and service all outstanding - then strolled thru the museum for some culture with a drink bf calling it a night. Next time would love to enjoy the pool, hot tub and spa!

5.0/512 Jan 2025

Patrice

I had a great stay. The property was very unique. I loved the museum and decor. The restaurant and bar had great food. I also enjoyed the fitness and pool areas. If I’m in the city I would stay again.

5.0/512 Jan 2025

Jerrod • Couple Trip

One of the best hotel chains around. Amazing gallery spaces and swell rooms. Don't miss the restaurant and cafe.

5.0/54 Jan 2025

regine

Beautiful property! Loved the decor. The rooms we chose was large (2 beds) and comfortable. Very clean and modern. Great bar! Mason is a great bartender!

5.0/53 Jan 2025

Victoria

We love staying here because on top of being super nice, it’s an easy walk to a Blues game. Love the bar & the coffee shop on sight, also.

5.0/52 Jan 2025

Elizabeth • Couple Trip

Love this concept and everything was great . Cool building , great food , lovely staff. Room was big. Best of St. Louis !

5.0/51 Jan 2025

Denise

Fabulous hotel, decor amazing, loved the museum, room was perfect

5.0/51 Jan 2025

Pearlie

The museum

5.0/51 Jan 2025

Bryant • Couple Trip

Everything was amazing and accommodating

5.0/51 Jan 2025

Madison • Couple Trip

This hotel exceeded our expectations in every way. Check in was quick and easy with friendly hotel, museum, and wait staff. The property is beautiful. The rooms are incredibly clean and have a sleek, modern feel. I especially appreciate their efforts to make the hotel experience more sustainable with reclaimed materials, eco friendly amenities, and skipping out on cheap one-off products (travel size toiletries) for bottles that stay in the room and I assume are refilled rather than tossed when empty. The pool is a proper 25yard pool that you can swim laps in. The gym is extensive and is open 24 hours. Both place include water taps in case you work up a thirst. Steam rooms, a sauna, and waterfall showers are located near the pool. Overall this hotel is an incredible experience at a reasonable price. Perfect for a weekend getaway, a special occasion, or a holiday. I cannot recommend 21C hotels enough. My partner and I plan on visiting other locations in the future and will go out of our way to book with them when possible.

5.0/530 Dec 2024

Pam

I had reserved two rooms. Both double queen beds. Called because I wanted to reassure these were near each other. Told no but I could change out one double queen doom for a king and they would be directly across from each other. Well that ended up not being the case. Down the hall and around a corner. Disappointed because I would have kept the original reservations because the king room is quite small in comparison but was willing to switch with rooms directly across. And then they were not. The hotel was beautiful. Very clean.

5.0/530 Dec 2024

Verified traveler

It was a wonderful surprise-exceeded expectations.

5.0/530 Dec 2024

Carmen Lanette • Couple Trip

Loved the restaurant and cafe. Staff were friendly and welcoming. Unique artsy environment. Looking forward to returning.

5.0/524 Dec 2024

Amandine • Family Trip

Clean, no smell, excellent!

5.0/523 Dec 2024

Lenore

Absolutely beautiful hotel. Great staff too!

5.0/521 Dec 2024

Jennifer

21C amazing as always!! l look for a 21C first anytime l travel for an overnight stay l don't feel like l'm in a hotel for the night, but instead feel transported to an experience that brings beauty and comfort to my stay with their attention to details and onsite art gallery; and provides delicious and satisfying cocktails and food with their amazing lounges and restaurants. Rooms are roomy, stylishly decorated, comfortable and have ample amenities. Staff is always welcoming and helpful. Shout out to St Louis 21C for my new annual Christmas overnight travel tradition and present to myself as l drive from Columbus OH to Ft Smith AR! Thank you for always making it the best! Bring a 21C to Columbus!

5.0/517 Dec 2024

Andy • Family Trip

We loved the atmosphere of every space. First class in every aspect, we have never seen such detail put in on everything from the soaps and custom furnishings. There was nothing second rate in your design choices, made our stay special!

Popular Facilities

WiFi

Fitness Center

tiket Green

Spa

24-hour Front Desk

Elevator

Meeting Facilities

Sports, Spa, & Recreations

Pool Table

Fitness Facilities

Billiards

Public Facilities

ATM/Banking

Elevator/Lift

Vending Machine

Hotel Services

Laundry Service/Dry Cleaning

Luggage Storage

Concierge Services

24-hour Front Desk

Other Facilities

tiket Green

Business Facilities

Meeting Rooms

Business Center

Ballroom

Health & Medical

Spa

Steam Room

Accesibility

Accessibility Equipment

Wheelchair Accessible

Hotel Policy

Smoke-free Property

Transportation

Valet Parking (Surcharge)

Connectivity

Free WiFi

Location

See maps

1528 Locust street, St. Louis, Missouri, US

Nearby Destinations

Central Public Library

Other landmarks

359m

St. Louis Children's Aquarium/World Aquarium

Water parks & amusement parks

372m

St. Louis Gateway Station

Train stations

1km

Laclede's Landing

Shopping areas

2km

Laclede's Landing

Shopping areas

2km

Soulard Farmer's Market

Shopping areas

3km

Saint Louis Galleria Mall

Shopping areas

Other landmarks

4.6km

Barnes Jewish Hospital

Hospitals

7km

All distances are measured in straight lines. The actual travel distance may be different.

Accommodation Policy

Check-in Procedure

Check-in4:00 PM-11:00 AM

Check-out11:00 AM

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Safety features at this property include a smoke detector and outdoor lighting

Front desk staff will greet guests on arrival at the property.

Want to check in early? Fill out the Special Requests form on the booking page.

More Policies

Reservations are required for massage services. Reservations can be made by contacting the hotel prior to arrival, using the contact information on the booking confirmation.
This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

About 21C Museum Hotel St Louis

21C Museum Hotel St Louis Location
A stay at 21C Museum Hotel St Louis places you in the heart of St. Louis, within a 10-minute walk of Enterprise Center and City Museum. This luxury hotel is 0.6 mi (1 km) from St. Louis Union Station and 0.7 mi (1.1 km) from America's Center Convention Complex.

21C Museum Hotel St Louis Facility and Service
Don't miss out on the many recreational opportunities, including an indoor pool, a steam room, and a fitness center. Additional amenities at this hotel include complimentary wireless internet access, concierge services, and a banquet hall.

21C Museum Hotel St Louis Rooms
Make yourself at home in one of the 104 air-conditioned rooms featuring espresso makers and flat-screen televisions. Complimentary wireless internet access keeps you connected, and cable programming is available for your entertainment. Bathrooms have complimentary toiletries and hair dryers. Conveniences include phones, as well as safes and desks.

Restaurant and Cafe
Enjoy a meal at the restaurant or snacks in the coffee shop/cafe. The hotel also offers room service (during limited hours). Wrap up your day with a drink at the bar/lounge. Cooked-to-order breakfasts are available daily from 6:30 AM to 1:00 PM for a fee.

Frequently Asked Questions

What is the address of 21C Museum Hotel St Louis?

What are the standard check-in & check-out times of 21C Museum Hotel St Louis?

What are the facilities available in 21C Museum Hotel St Louis?

Room Type and Price

Fri, 25 Apr 2025 - Sat, 26 Apr 2025 (1 night)

1 Room, 1 Guest

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Perfect for solo trips

Best pick for you!

Bunk Room

Refund & reschedule not allowed

25.0m², 1 guest, 1 bunk bed

Total (1 Room, 1 night)

USD 239

(after taxes: USD 279)

Room (Bunk Bed)

1/8

Free Wi-Fi

Bunk Room

Refund & reschedule not allowed

1 Guest

1 bunk bed

Breakfast not included

Free Wi-Fi

USD 239

/room/night (after taxes: USD 279)

Room (Bunk Bed)

100% Refund & Reschedule until 24 Apr 2025

1 Guest

1 Twin Bunk Bed

Breakfast not included

Free Wi-Fi

USD 239

/room/night (after taxes: USD 279)

Bunk Room

100% Refund & Reschedule until 24 Apr 2025

1 Guest

1 bunk bed

Breakfast not included

Wi-Fi

Pay at Hotel

Only 1 rooms left!

USD 239

/room/night (after taxes: USD 289)

Deluxe Room

1/26

28m²

Free Wi-Fi

Deluxe King

Refund & reschedule not allowed

1 Guest

King

Breakfast not included

Free Wi-Fi

USD 249

/room/night (after taxes: USD 291)

Deluxe Room, 1 King Bed

100% Refund & Reschedule until 24 Apr 2025

1 Guest

1 King Bed

Breakfast not included

Free Wi-Fi

USD 249

/room/night (after taxes: USD 291)

Deluxe King Accessible

100% Refund & Reschedule until 24 Apr 2025

1 Guest

King

Breakfast not included

Wi-Fi

Pay at Hotel

Only 1 rooms left!

USD 249

/room/night (after taxes: USD 301)

Deluxe Room

1/30

Free Wi-Fi

Deluxe Room, Accessible (Accessible)

100% Refund & Reschedule until 24 Apr 2025

1 Guest

King

Breakfast not included

Free Wi-Fi

USD 249

/room/night (after taxes: USD 291)

Deluxe Room

1/17

34m²

Free Wi-Fi

Deluxe Double Room, 2 Queen Beds

100% Refund & Reschedule until 24 Apr 2025

1 Guest

2 Queen Beds

Breakfast not included

Free Wi-Fi

USD 259

/room/night (after taxes: USD 303)

Deluxe Double Queen

Refund & reschedule not allowed

1 Guest

Queen

Breakfast not included

Free Wi-Fi

USD 259

/room/night (after taxes: USD 303)

Deluxe Double Queen

100% Refund & Reschedule until 24 Apr 2025

1 Guest

2 Queen-size bed 150-154 width

Breakfast not included

Wi-Fi

USD 310

/room/night (after taxes: USD 344)

Room, 1 King Bed, Corner

1/16

30m²

Free Wi-Fi

Room, 1 King Bed, Corner

100% Refund & Reschedule until 24 Apr 2025

1 Guest

1 King Bed

Breakfast not included

Free Wi-Fi

USD 259

/room/night (after taxes: USD 303)

Corner King

Refund & reschedule not allowed

1 Guest

King

Breakfast not included

Free Wi-Fi

USD 259

/room/night (after taxes: USD 303)

Corner King

100% Refund & Reschedule until 24 Apr 2025

1 Guest

King

Breakfast not included

Wi-Fi

Pay at Hotel

USD 259

/room/night (after taxes: USD 313)

Queen Deluxe Room

1/5

34m²

Free Wi-Fi

Deluxe Queen Room

100% Refund & Reschedule until 24 Apr 2025

1 Guest

Queen

Breakfast not included

Wi-Fi

USD 259

/room/night (after taxes: USD 313)

Deluxe Queen Room

100% Refund & Reschedule until 24 Apr 2025

1 Guest

Queen

Breakfast not included

Wi-Fi

Pay at Hotel

USD 259

/room/night (after taxes: USD 313)

Luxury Double Room, 2 Queen Beds

1/12

38m²

Free Wi-Fi

Luxury Double Room, 2 Queen Beds

100% Refund & Reschedule until 24 Apr 2025

1 Guest

2 Queen Beds

Breakfast not included

Free Wi-Fi

USD 279

/room/night (after taxes: USD 326)

Luxury Double Queen

Refund & reschedule not allowed

1 Guest

2 Queen

Breakfast not included

Free Wi-Fi

USD 279

/room/night (after taxes: USD 326)

Luxury Double Queen

100% Refund & Reschedule until 24 Apr 2025

1 Guest

Double

Breakfast not included

Wi-Fi

USD 334

/room/night (after taxes: USD 371)

Queen Room

1/4

38m²

Free Wi-Fi

Luxury Queen Room

100% Refund & Reschedule until 24 Apr 2025

1 Guest

Queen

Breakfast not included

Wi-Fi

USD 279

/room/night (after taxes: USD 337)

Luxury Queen Room

100% Refund & Reschedule until 24 Apr 2025

1 Guest

Queen

Breakfast not included

Wi-Fi

Pay at Hotel

USD 279

/room/night (after taxes: USD 337)

Loft Double Queen

1/11

Free Wi-Fi

Loft Double Queen

Refund & reschedule not allowed

1 Guest

2 Queen

Breakfast not included

Free Wi-Fi

USD 289

/room/night (after taxes: USD 338)

Loft Double Queen

100% Refund & Reschedule until 24 Apr 2025

1 Guest

2 Queen

Breakfast not included

Wi-Fi

Pay at Hotel

Only 1 rooms left!

USD 289

/room/night (after taxes: USD 349)

Loft Double Queen

100% Refund & Reschedule until 24 Apr 2025

1 Guest

2 Queen-size bed 150-154 width

Breakfast not included

Wi-Fi

USD 346

/room/night (after taxes: USD 384)

Loft, 2 Queen Beds

1/30

Free Wi-Fi

Loft, 2 Queen Beds

100% Refund & Reschedule until 24 Apr 2025

1 Guest

2 Queen

Breakfast not included

Free Wi-Fi

USD 289

/room/night (after taxes: USD 338)

2 Bedroom Suite

1/15

Deluxe King Suite with Roll-In Shower - Accessible

100% Refund & Reschedule until 24 Apr 2025

1 Guest

King

Breakfast not included

Wi-Fi

Only 1 rooms left!

USD 369

/room/night (after taxes: USD 444)

Deluxe King Suite with Roll-In Shower - Accessible

100% Refund & Reschedule until 24 Apr 2025

1 Guest

King

Breakfast not included

Wi-Fi

Pay at Hotel

Only 1 rooms left!

USD 369

/room/night (after taxes: USD 444)

Suite

1/30

Free Wi-Fi

Luxury King Suite

Refund & reschedule not allowed

1 Guest

King

Breakfast not included

Wi-Fi

Only 1 rooms left!

USD 569

/room/night (after taxes: USD 682)

Luxury King Suite

Refund & reschedule not allowed

1 Guest

King

Breakfast not included

Wi-Fi

Pay at Hotel

Only 1 rooms left!

USD 569

/room/night (after taxes: USD 682)

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