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Exterior & Views 1, Residence Inn By Marriott Jacksonville - Mayo Clinic Area, Duval
Bedroom 2, Residence Inn By Marriott Jacksonville - Mayo Clinic Area, Duval
Bathroom 3, Residence Inn By Marriott Jacksonville - Mayo Clinic Area, Duval
Food & Drinks 4, Residence Inn By Marriott Jacksonville - Mayo Clinic Area, Duval
Sport & Beauty, Residence Inn By Marriott Jacksonville - Mayo Clinic Area, Duval
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Hotel

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Duval, Florida

The Fun Awaits

Tourist attractions nearby
Tourist attractions nearbyOnly 4.9 km to Adventure Landing
Near healthcare facilities
Near healthcare facilitiesOnly 1.3 km to Mayo Clinic Florida
Suitable for your business trip
Suitable for your business tripStay productive with a dedicated workspace and business facilities.

Reviews

See all
4.7/5
FantasticFrom 194 reviews
5.0/57 Apr 2025
Andrea
This hotel was better than expected. Studio suite had everything needed for an extended stay including a full size cridhe, dishwasher cookware, dishes.Room was clean and comfortable. Staff were friendly and complimentary breakfast was good with options.
5.0/57 Apr 2025
Andrea
This hotel was better than expected. Studio suite had everything needed for an extended stay including a full size cridhe, dishwasher cookware, dishes.Room was clean and comfortable. Staff were friendly and complimentary breakfast was good with options.
5.0/56 Apr 2025
Verified traveler
I had a terrible next-door neighbor family, whose kids were extremely loud obnoxious from 1030pm until 1:30 AM. Next morning, I requested a change of room and the staff, especially the front desk, guy named Michael. He was very accommodating and moved to another room. He also drives a shuttle from Hotel to Mayo Clinic, where I had to go for a couple of procedures. He is really an exceptional staff person. One thing I would recommend is one day people who are paying customers, and they have to move from one room to another not because they want to, but they have no choice. The staff from Hotel should be able to help move the staff. They have an offer that even though they were walking with me to move me from one room to another. I moved all my stuff by myself
5.0/56 Apr 2025
Verified traveler
I had a terrible next-door neighbor family, whose kids were extremely loud obnoxious from 1030pm until 1:30 AM. Next morning, I requested a change of room and the staff, especially the front desk, guy named Michael. He was very accommodating and moved to another room. He also drives a shuttle from Hotel to Mayo Clinic, where I had to go for a couple of procedures. He is really an exceptional staff person. One thing I would recommend is one day people who are paying customers, and they have to move from one room to another not because they want to, but they have no choice. The staff from Hotel should be able to help move the staff. They have an offer that even though they were walking with me to move me from one room to another. I moved all my stuff by myself
5.0/530 Mar 2025
Raul Alexander
Excellent
5.0/530 Mar 2025
Raul Alexander
Excellent
5.0/528 Mar 2025
Sara • Couple Trip
Great place highly recommend
5.0/528 Mar 2025
Sara • Couple Trip
Great place highly recommend
5.0/527 Mar 2025
John • Family Trip
Q at the front desk was the absolute best. She went out of her way everyday to help us.
5.0/527 Mar 2025
John • Family Trip
Q at the front desk was the absolute best. She went out of her way everyday to help us.
5.0/519 Mar 2025
David • Couple Trip
The property close to Mayo Clinic. I liked the kitchens if you need to stay long.
5.0/519 Mar 2025
David • Couple Trip
The property close to Mayo Clinic. I liked the kitchens if you need to stay long.
5.0/517 Mar 2025
Mario • Couple Trip
Only thing I would change is the bar and restaurant area. A bit awkward but understandable that most people just want to go to their room. We were there 2 solid weeks but could have used a beer after 12 hours days of scans and treatments but maybe that is just us. We only ate out once at Joes crab which cost over $100 with just one beer??? Better value at the hotel. Or uber eat.
5.0/517 Mar 2025
Mario • Couple Trip
Only thing I would change is the bar and restaurant area. A bit awkward but understandable that most people just want to go to their room. We were there 2 solid weeks but could have used a beer after 12 hours days of scans and treatments but maybe that is just us. We only ate out once at Joes crab which cost over $100 with just one beer??? Better value at the hotel. Or uber eat.
5.0/57 Mar 2025
Gerard
This hotel has many patients that go to Mayo Clinic stay. There is not adequate. Handicap parking. I stay there often and almost always need to park on the side of the building and walk. Also the room service is a nice addition. A suggestion would be to have a direct line to call the restaurant to place orders, currently you need to call the front desk.
5.0/57 Mar 2025
Gerard
This hotel has many patients that go to Mayo Clinic stay. There is not adequate. Handicap parking. I stay there often and almost always need to park on the side of the building and walk. Also the room service is a nice addition. A suggestion would be to have a direct line to call the restaurant to place orders, currently you need to call the front desk.
5.0/524 Feb 2025
Karen • Couple Trip
Very convenient while visiting Mayo Jacksonville. Easy access from the highway and the morning breakfast was pretty good.
5.0/524 Feb 2025
Karen • Couple Trip
Very convenient while visiting Mayo Jacksonville. Easy access from the highway and the morning breakfast was pretty good.
5.0/518 Feb 2025
Verified traveler
Quiet, updated, comfortable.
5.0/518 Feb 2025
Verified traveler
Quiet, updated, comfortable.

Location

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4905 SAN PABLO ROAD SOUTH, Jacksonville, Florida, US
All distances are measured in straight lines. The actual travel distance may be different.

Accommodation Rules

Check-in Procedure
Check-in4:00 PM-6:00 AM
Check-out11:00

  • Extra-person charges may apply and vary depending on property policy
  • Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
  • Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
  • This property accepts credit cards; cash is not accepted
  • Cashless transactions are available
  • Safety features at this property include a carbon monoxide detector, a fire extinguisher, a smoke detector, and window guards

If you are planning to arrive after 11:00 PM please contact the property in advance using the information on the booking confirmation. Front desk staff will greet guests on arrival at the property. Information provided by the property may be translated using automated translation tools.

See more

Want to check in early? Fill out the Special Requests form on the booking page.

More Policies
  • Only registered guests are allowed in the guestrooms.
  • The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation.
  • Guests can arrange to bring pets by contacting the property directly, using the contact information on the booking confirmation (surcharges apply and can be found in the Fees section).
  • Cashless payment methods are available for all transactions and guests can access their rooms with a mobile device.
  • Contactless check-in and contactless check-out are available.
  • This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

About Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Residence Inn By Marriott Jacksonville - Mayo Clinic Area Location
With a stay at Residence Inn By Marriott Jacksonville - Mayo Clinic Area in Jacksonville (Isle of Palms), you'll be a 1-minute drive from Mayo Clinic Florida and 9 minutes from St. Johns Town Center. This hotel is 10.3 mi (16.5 km) from Mayport Naval Station and 5.2 mi (8.4 km) from University of North Florida.

Residence Inn By Marriott Jacksonville - Mayo Clinic Area Facility and Service
Be sure to enjoy recreational amenities including an outdoor pool and a 24-hour fitness center. This hotel also features complimentary wireless internet access, concierge services, and wedding services.

Residence Inn By Marriott Jacksonville - Mayo Clinic Area Rooms
Make yourself at home in one of the 155 air-conditioned rooms featuring kitchens with refrigerators and stovetops. 55-inch Smart televisions with cable programming provide entertainment, while complimentary wireless internet access keeps you connected. Conveniences include phones, as well as laptop-compatible safes and desks.

Restaurant and Cafe
Grab a bite from the grocery/convenience store serving guests of Residence Inn By Marriott Jacksonville - Mayo Clinic Area. Relax with your favorite drink at the bar/lounge or the poolside bar. A complimentary buffet breakfast is served on weekdays from 6:30 AM to 9:00 AM and on weekends from 7:00 AM to 9:30 AM.

Room Type and Price

Fri, 13 Nov 2026 - Sat, 14 Nov 2026 (1 night)
1 Room, 1 Adult, 0 Children