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Exterior & Views 1, Residence Inn Durham McPherson/Duke University Medical Cntr, Durham
Public Area 2, Residence Inn Durham McPherson/Duke University Medical Cntr, Durham
Bedroom 3, Residence Inn Durham McPherson/Duke University Medical Cntr, Durham
Bathroom 4, Residence Inn Durham McPherson/Duke University Medical Cntr, Durham
Food & Drinks 5, Residence Inn Durham McPherson/Duke University Medical Cntr, Durham
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Hotel

Residence Inn Durham McPherson/Duke University Medical Cntr

Durham, North Carolina

The Fun Awaits

Tourist attractions nearby
Tourist attractions nearbyOnly 1.5 km to Durham Performing Arts Center
Nice location! Near public transport
Nice location! Near public transportOnly 890 m to Durham Station
Near healthcare facilities
Near healthcare facilitiesOnly 3.1 km to Durham VA Medical Center
Suitable for your business trip
Suitable for your business tripStay productive with business facilities.

Reviews

See all
4.3/5
GoodFrom 100 reviews
5.0/531 May 2026
Diana • Couple Trip
The rooms are spacious and the location is great in downtown Durham. Easy walk to Duke east. Several good restaurants and ice cream are just a block away. There's a charge for parking here. Breakfast was tasty. I would stay here again.
5.0/531 May 2026
Shelly • Family Trip
Room was very spacious, staff very friendly
5.0/523 May 2026
Jeff • Family Trip
Very clean and spacious room. Hotel staff that I had contact with were very hospitable and professional.
5.0/523 May 2026
Athena • Couple Trip
I had a great stay overall. The service was excellent, and the staff was incredibly friendly, welcoming, and helpful throughout my visit. They really made the experience enjoyable. Rooms are spacious and beds are comfortable. The only area that could use improvement is the breakfast. The selection was very basic, mostly eggs and pork options, with limited healthier choices available. The fruit also did not seem very fresh. I think revamping the breakfast menu with fresher ingredients and more healthy variety would make the stay even better. Despite that, I would still recommend this hotel because the customer service was outstanding.
5.0/521 May 2026
Tiffany • Family Trip
Clean, spacious rooms with an extremely helpful staff! Highly recommended!!
5.0/522 Mar 2026
RICHARD
Great downtown location
5.0/520 Feb 2026
Syreeta • Couple Trip
Rooms were spacious and spotless. Customer Service was phenomenal! Housekeeping were friendly and had no problems giving the extra items needed, including extra pillows.
5.0/53 Jan 2026
David • Couple Trip
We love this hotel. The staff is excellent and the rooms are well designed and comfortable. The breakfast is delicious.
5.0/52 Jan 2026
Anna F • Solo Trip
Courteous staff, spotless rooms, comfortable bed and pillows.
5.0/59 Nov 2025
Lisa
Hotel was great - very friendly staff.
5.0/58 Nov 2025
Tim
Great stay. The hotel breakfast left a little something to be desired but the room was clean, the staff was helpful. This was everything I expected.
5.0/527 Sep 2025
Anthony • Family Trip
Yes
5.0/55 Aug 2025
Derek
Was very nice. The staff was very polite when we arrived.
5.0/529 Jul 2025
Melissa
Staff was amazing! Breakfast had so many options, quiche, waffles, fresh fruit, sausage, hard boiled eggs…. Room was very clean. Small market store in lobby. Lobby area with a tv and tons of seating. Nice workout room. But again, staff was incredible!
5.0/526 Jul 2025
Ronnie A.
We had an issue with the room but the district manager took care of it immediately. Excellent Team
5.0/519 Jul 2025
Kaiqing
All good as expected
5.0/526 Jun 2025
LaMeesha • Solo Trip
I am thankful for the very hospitable staff that I encountered at the hotel. Everyone was smiling at the front desk every time I passed by.
5.0/59 Jun 2025
Timmy
It was very clean and the staff was excellent. The stay was really good. The attendant was great at checking.
5.0/531 May 2025
David • Family Trip
We love staying here when we come to visit our family. Every stay has been wonderful. The room is very comfortable. We love the gym and the breakfasts. Having a nice laundry area on the premises is also a huge plus. The best part is the fantastic staff-everyone is so nice and helpful. Thank you for always making our trips memorable.
5.0/510 May 2025
Reed • Solo Trip
The place to stay if you have business at Duke. Housekeeping is hit-or-miss, but that's par for the course for an extended-stay hotel.

Location

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1108 West Main Street, Durham, North Carolina, US
All distances are measured in straight lines. The actual travel distance may be different.

Accommodation Rules

Check-in Procedure
Check-in3:00 PM-midnight
Check-out12:00

  • Extra-person charges may apply and vary depending on property policy
  • Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
  • Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
  • This property accepts credit cards; cash is not accepted
  • Safety features at this property include a carbon monoxide detector, a fire extinguisher, and a smoke detector

Front desk staff will greet guests on arrival at the property. Information provided by the property may be translated using automated translation tools.

See more

Want to check in early? Fill out the Special Requests form on the booking page.

More Policies
  • Guests can arrange to bring pets by contacting the property directly, using the contact information on the booking confirmation (surcharges apply and can be found in the Fees section).
  • Contactless check-out is available.
  • This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

About Residence Inn Durham McPherson/Duke University Medical Cntr

Residence Inn Durham McPherson/Duke University Medical Cntr Location
Located in Durham (Trinity Park), Residence Inn Durham McPherson/Duke University Medical Cntr is steps from Duke University and a 4-minute drive from Duke University Hospital. This hotel is 7.3 mi (11.7 km) from Research Triangle Park and 8.6 mi (13.8 km) from Streets at Southpoint Mall.

Residence Inn Durham McPherson/Duke University Medical Cntr Facility and Service
Enjoy recreation amenities such as a 24-hour fitness center or take in the view from a terrace. This hotel also features complimentary wireless internet access, concierge services, and wedding services. Guests can catch a ride to nearby destinations on the complimentary area shuttle.

Residence Inn Durham McPherson/Duke University Medical Cntr Rooms
Make yourself at home in one of the 147 guestrooms, featuring kitchens with full-sized refrigerators/freezers and stovetops. 32-inch Smart televisions with cable programming provide entertainment, while complimentary wireless internet access keeps you connected. Conveniences include safes and desks, as well as phones with free local calls.

Restaurant and Cafe
Grab a bite from the grocery/convenience store serving guests of Residence Inn Durham McPherson/Duke University Medical Cntr. A complimentary on-the-go breakfast is served daily from 7:00 AM to 9:00 AM.

Room Type and Price

Thu, 15 Oct 2026 - Fri, 16 Oct 2026 (1 night)
1 Room, 1 Adult, 0 Children