Hotels in Cape Girardeau
Showing 25 hotels in Cape Girardeau
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Drury Inn & Suites Jackson MO
Drury Inn & Suites Jackson MO Location
With a stay at Drury Inn & Suites Jackson MO, you'll be centrally located in Jackson, within a 10-minute drive of Cape Girardeau Conservation Nature Center and Saint Francis Healthcare System. This hotel is 10.2 mi (16.5 km) from Mississippi River and 10.4 mi (16.7 km) from Shawnee National Forest.
Drury Inn & Suites Jackson MO Facility and Service
Take advantage of recreational opportunities offered, including an indoor pool, a hot tub, and a fitness center. Additional features at this hotel include complimentary wireless internet access, a television in a common area, and a banquet hall.
Drury Inn & Suites Jackson MO Rooms
Make yourself at home in one of the 80 guestrooms featuring refrigerators and microwaves. LCD televisions with cable programming provide entertainment, while complimentary wireless internet access keeps you connected. Private bathrooms with shower/tub combinations feature complimentary toiletries and hair dryers. Conveniences include desks and separate sitting areas, as well as phones with free local calls.
Restaurant and Cafe
Meet other guests and eat at the complimentary reception. A complimentary buffet breakfast is served on weekdays from 6:00 AM to 9:00 AM and on weekends from 7:00 AM to 10:00 AM.
See detailsWith a stay at Drury Inn & Suites Jackson MO, you'll be centrally located in Jackson, within a 10-minute drive of Cape Girardeau Conservation Nature Center and Saint Francis Healthcare System. This hotel is 10.2 mi (16.5 km) from Mississippi River and 10.4 mi (16.7 km) from Shawnee National Forest.
Drury Inn & Suites Jackson MO Facility and Service
Take advantage of recreational opportunities offered, including an indoor pool, a hot tub, and a fitness center. Additional features at this hotel include complimentary wireless internet access, a television in a common area, and a banquet hall.
Drury Inn & Suites Jackson MO Rooms
Make yourself at home in one of the 80 guestrooms featuring refrigerators and microwaves. LCD televisions with cable programming provide entertainment, while complimentary wireless internet access keeps you connected. Private bathrooms with shower/tub combinations feature complimentary toiletries and hair dryers. Conveniences include desks and separate sitting areas, as well as phones with free local calls.
Restaurant and Cafe
Meet other guests and eat at the complimentary reception. A complimentary buffet breakfast is served on weekdays from 6:00 AM to 9:00 AM and on weekends from 7:00 AM to 10:00 AM.
“Great deal”
Quality Inn Cape Girardeau North
Quality Inn Cape Girardeau North Location
With a stay at Quality Inn Cape Girardeau North in Cape Girardeau, you'll be within a 10-minute drive of Shawnee National Forest and Mississippi River. This hotel is 0.6 mi (1 km) from Saint Francis Healthcare System and 0.9 mi (1.4 km) from Cape Splash Family Aquatic Center.
Quality Inn Cape Girardeau North Facility and Service
Take advantage of recreation opportunities such as an outdoor pool, or other amenities including complimentary wireless internet access and a television in a common area.
Quality Inn Cape Girardeau North Rooms
Make yourself at home in one of the 49 air-conditioned guestrooms. Your memory foam bed comes with down comforters and Egyptian cotton sheets. Complimentary wireless internet access keeps you connected, and cable programming is available for your entertainment. Bathrooms feature shower/tub combinations, complimentary toiletries, and hair dryers.
Restaurant and Cafe
A complimentary continental breakfast is served on weekdays from 6:00 AM to 9:00 AM and on weekends from 7:00 AM to 10:00 AM.
See detailsWith a stay at Quality Inn Cape Girardeau North in Cape Girardeau, you'll be within a 10-minute drive of Shawnee National Forest and Mississippi River. This hotel is 0.6 mi (1 km) from Saint Francis Healthcare System and 0.9 mi (1.4 km) from Cape Splash Family Aquatic Center.
Quality Inn Cape Girardeau North Facility and Service
Take advantage of recreation opportunities such as an outdoor pool, or other amenities including complimentary wireless internet access and a television in a common area.
Quality Inn Cape Girardeau North Rooms
Make yourself at home in one of the 49 air-conditioned guestrooms. Your memory foam bed comes with down comforters and Egyptian cotton sheets. Complimentary wireless internet access keeps you connected, and cable programming is available for your entertainment. Bathrooms feature shower/tub combinations, complimentary toiletries, and hair dryers.
Restaurant and Cafe
A complimentary continental breakfast is served on weekdays from 6:00 AM to 9:00 AM and on weekends from 7:00 AM to 10:00 AM.
Drury Inn & Suites Cape Girardeau
Drury Inn & Suites Cape Girardeau Location
With a stay at Drury Inn & Suites Cape Girardeau, you'll be centrally located in Cape Girardeau, within a 10-minute drive of Shawnee National Forest and Mississippi River. This hotel is 1.2 mi (2 km) from Saint Francis Medical Center and 2.7 mi (4.3 km) from Saint Francis Healthcare System.
Drury Inn & Suites Cape Girardeau Facility and Service
Be sure to enjoy recreational amenities, including an indoor pool, a hot tub, and a fitness center. Additional features at this hotel include complimentary wireless internet access, a television in a common area, and a banquet hall.
Drury Inn & Suites Cape Girardeau Rooms
Make yourself at home in one of the 87 guestrooms featuring refrigerators and LCD televisions. Complimentary wireless internet access keeps you connected, and cable programming is available for your entertainment. Private bathrooms with shower/tub combinations feature complimentary toiletries and hair dryers. Conveniences include desks and separate sitting areas, as well as phones with free local calls.
Restaurant and Cafe
Meet other guests and eat at the complimentary reception. A complimentary buffet breakfast is served on weekdays from 6:00 AM to 9:00 AM and on weekends from 7:00 AM to 10:00 AM.
Important Information
The following facilities or services will be unavailable from August 10 2026 to August 21 2026 (dates subject to change):
See detailsWith a stay at Drury Inn & Suites Cape Girardeau, you'll be centrally located in Cape Girardeau, within a 10-minute drive of Shawnee National Forest and Mississippi River. This hotel is 1.2 mi (2 km) from Saint Francis Medical Center and 2.7 mi (4.3 km) from Saint Francis Healthcare System.
Drury Inn & Suites Cape Girardeau Facility and Service
Be sure to enjoy recreational amenities, including an indoor pool, a hot tub, and a fitness center. Additional features at this hotel include complimentary wireless internet access, a television in a common area, and a banquet hall.
Drury Inn & Suites Cape Girardeau Rooms
Make yourself at home in one of the 87 guestrooms featuring refrigerators and LCD televisions. Complimentary wireless internet access keeps you connected, and cable programming is available for your entertainment. Private bathrooms with shower/tub combinations feature complimentary toiletries and hair dryers. Conveniences include desks and separate sitting areas, as well as phones with free local calls.
Restaurant and Cafe
Meet other guests and eat at the complimentary reception. A complimentary buffet breakfast is served on weekdays from 6:00 AM to 9:00 AM and on weekends from 7:00 AM to 10:00 AM.
Important Information
The following facilities or services will be unavailable from August 10 2026 to August 21 2026 (dates subject to change):
- Hot tub
- Swimming pool
“Great deal”
Courtyard By Marriott Cape Girardeau Downtown
Experience the character of a thoughtfully restored property at our hotel in downtown Cape Girardeau, where historic charm blends seamlessly with modern comfort. Our Cape Girardeau, MO hotel places you steps from local restaurants, unique bars, and cultural destinations, along with convenient access to the Southeast Missouri State University campus. You can start or end your day at The Bistro, offering balanced breakfast and dinner options alongside a full bar featuring a curated bourbon selection. After exploring the neighborhood, retreat to well‑designed guest rooms and suites with plush bedding and city views that create a relaxing space to unwind. A spacious 24‑hour fitness center helps you stay on track with your routine. Our family friendly hotel in downtown Cape Girardeau, will be loved by adults and children of all ages. The property also provides versatile event space ideal for small to mid‑sized meetings. Your stay at Courtyard Cape Girardeau Downtown is crafted for comfort and ease.
See detailsHoliday Inn Express & Suites CAPE GIRARDEAU I-55 by IHG
Welcome to Our Cape Girardeau Hotel. Just off I- 55 at exit 96, the Holiday Inn Express Hotel & Suites Cape Girardeau I-55 offers hotel guests 102 spacious, contemporary suites. Vacation and business guests alike choose these accommodations for a comfortable and convenient stay. Our Cape Girardeau, Missouri hotel is just minutes from Southeast Missouri State University, where guests are encouraged to cheer on the Redhawks in football and basketball. We're also only 10 miles from Trail of Tears State Park, so families can enjoy picnics, hiking, biking and fishing. Be sure to stop by our Old Downtown area where you will not only enjoy a variety of shops and restaurants, but you can enjoy the great view of the Mississippi River. Business travelers appreciate our Cape Girardeau, Missouri hotel's convenient location close to St. Francis Hospital, Southeast Missouri Hospital, Doctors Park, the Show Me Center, Procter & Gamble, Mondi, Shawnee Park and Biokyowa. We provide two spacious meeting rooms, as well, which feature A/V equipment ideal for business functions or special events. With the help of our professional staff, your event can be a success. At our Girardeau hotel, we know it's the extra perks that make your stay unforgettable. We provide an indoor pool and well-equipped fitness center to help you relax and unwind. Be sure to stop by our breakfast bar each morning, too, for biscuits, eggs, fruit and our signature cinnamon rolls. We look forward to your next visit!
See details“Great deal”
Hampton Inn Cape Girardeau I 55 East
Hampton Inn Cape Girardeau I 55 East Location
With a stay at Hampton Inn Cape Girardeau I 55 East in Cape Girardeau, you'll be within a 10-minute drive of Shawnee National Forest and Mississippi River. This hotel is 0.5 mi (0.8 km) from Saint Francis Medical Center and 2.3 mi (3.7 km) from Saint Francis Healthcare System.
Hampton Inn Cape Girardeau I 55 East Facility and Service
Don't miss out on recreational opportunities including an indoor pool and a fitness center. Additional features at this hotel include complimentary wireless internet access, a picnic area, and a banquet hall.
Hampton Inn Cape Girardeau I 55 East Rooms
Make yourself at home in one of the 86 guestrooms featuring refrigerators and flat-screen televisions. Complimentary wired and wireless internet access keeps you connected, and cable programming provides entertainment. Private bathrooms with shower/tub combinations feature complimentary toiletries and hair dryers. Conveniences include safes and desks, as well as phones with free local calls.
Restaurant and Cafe
Grab a bite from the snack bar/deli serving guests of Hampton Inn Cape Girardeau I 55 East. A complimentary buffet breakfast is served daily from 6 AM to 10 AM.
See detailsWith a stay at Hampton Inn Cape Girardeau I 55 East in Cape Girardeau, you'll be within a 10-minute drive of Shawnee National Forest and Mississippi River. This hotel is 0.5 mi (0.8 km) from Saint Francis Medical Center and 2.3 mi (3.7 km) from Saint Francis Healthcare System.
Hampton Inn Cape Girardeau I 55 East Facility and Service
Don't miss out on recreational opportunities including an indoor pool and a fitness center. Additional features at this hotel include complimentary wireless internet access, a picnic area, and a banquet hall.
Hampton Inn Cape Girardeau I 55 East Rooms
Make yourself at home in one of the 86 guestrooms featuring refrigerators and flat-screen televisions. Complimentary wired and wireless internet access keeps you connected, and cable programming provides entertainment. Private bathrooms with shower/tub combinations feature complimentary toiletries and hair dryers. Conveniences include safes and desks, as well as phones with free local calls.
Restaurant and Cafe
Grab a bite from the snack bar/deli serving guests of Hampton Inn Cape Girardeau I 55 East. A complimentary buffet breakfast is served daily from 6 AM to 10 AM.
“Great deal”
Hampton Inn Cape Girardeau I-55 East
incredible service at our Cape Girardeau, MO hotel. From our daily free hot breakfast to our nightly cookie hour, Hampton Inn Cape Girardeau I-55 East makes you feel at home. Located on the southeast corner of I-55 and William Street, our hotel complex includes various shopping and dining options. Walk to seven restaurants within the complex such as Cracker Barrel, Texas Roadhouse and Panera Bread. This beautiful new hotel offers all the amenities you need while traveling. Start your day with a quick workout in the fitness room or with some laps in the heated indoor pool. Sit down to a free, hot breakfast served daily with items including fresh baked waffles, eggs, biscuits and gravy and rotating options. If you’re pressed for time, grab Hampton’s On the Run™ Breakfast Bags, available Monday through Friday. Stay connected to the office with free WiFi in every room or work in the business center with two computer terminals and printing capabilities. End your day at our nightly cookie hour with warm cookies, cold milk and friendly team members available for your questions or concerns. Rest comfortably on a clean and fresh Hampton bed® watching the 37-inch HDTV or with your laptop on the provided lap desk.
See detailsPear Tree Inn Cape Girardeau Near The Medical Cen
Ideally located in the prime touristic area of Cape Girardeau, Pear Tree Inn Cape Girardeau Near the Medical Cent promises a relaxing and wonderful visit. Featuring a complete list of amenities, guests will find their stay at the property a comfortable one. Free Wi-Fi in all rooms, 24-hour front desk, facilities for disabled guests, luggage storage, Wi-Fi in public areas are just some of the facilities on offer. Comfortable guestrooms ensure a good night's sleep with some rooms featuring facilities such as television LCD/plasma screen, internet access – wireless, internet access – wireless (complimentary), air conditioning, heating. The hotel offers various recreational opportunities. For reliable service and professional staff, Pear Tree Inn Cape Girardeau Near the Medical Cent caters to your needs.
See details“Worth it”
Courtyard by Marriott Cape Girardeau Downtown
Courtyard by Marriott Cape Girardeau Downtown Location
Located in Cape Girardeau, Courtyard by Marriott Cape Girardeau Downtown is within a 15-minute walk of Southeast Missouri State University and eDen Spa & Salon. This hotel is 0.5 mi (0.7 km) from Shawnee National Forest and 0.6 mi (1 km) from Century Casino & Hotel Cape Girardeau.
Courtyard by Marriott Cape Girardeau Downtown Facility and Service
Take advantage of recreation opportunities such as a 24-hour fitness center or take in the view from a terrace and a garden. This hotel also features complimentary wireless internet access and gift shops/newsstands.
Courtyard by Marriott Cape Girardeau Downtown Rooms
Make yourself at home in one of the 91 guestrooms featuring refrigerators. Your bed comes with down comforters and Egyptian cotton sheets. Complimentary wired and wireless internet access keeps you connected, and satellite programming provides entertainment. Private bathrooms with bathtubs or showers feature complimentary toiletries and hair dryers.
Restaurant and Cafe
Satisfy your appetite with American cuisine at The Bistro, a bistro which features a bar/lounge. Dining is also available at the coffee shop/cafe. Cooked-to-order breakfasts are served on weekdays from 6:30 AM to 9:30 AM and on weekends from 7:00 AM to 10:00 AM for a fee.
See detailsLocated in Cape Girardeau, Courtyard by Marriott Cape Girardeau Downtown is within a 15-minute walk of Southeast Missouri State University and eDen Spa & Salon. This hotel is 0.5 mi (0.7 km) from Shawnee National Forest and 0.6 mi (1 km) from Century Casino & Hotel Cape Girardeau.
Courtyard by Marriott Cape Girardeau Downtown Facility and Service
Take advantage of recreation opportunities such as a 24-hour fitness center or take in the view from a terrace and a garden. This hotel also features complimentary wireless internet access and gift shops/newsstands.
Courtyard by Marriott Cape Girardeau Downtown Rooms
Make yourself at home in one of the 91 guestrooms featuring refrigerators. Your bed comes with down comforters and Egyptian cotton sheets. Complimentary wired and wireless internet access keeps you connected, and satellite programming provides entertainment. Private bathrooms with bathtubs or showers feature complimentary toiletries and hair dryers.
Restaurant and Cafe
Satisfy your appetite with American cuisine at The Bistro, a bistro which features a bar/lounge. Dining is also available at the coffee shop/cafe. Cooked-to-order breakfasts are served on weekdays from 6:30 AM to 9:30 AM and on weekends from 7:00 AM to 10:00 AM for a fee.
“Great deal”
Comfort Suites Jackson-Cape Girardeau
Comfort Suites Jackson-Cape Girardeau Location
With a stay at Comfort Suites Jackson-Cape Girardeau, you'll be centrally located in Jackson, within a 15-minute drive of Shawnee National Forest and Mississippi River. This hotel is 1.5 mi (2.5 km) from Cape Girardeau Conservation Nature Center and 2.8 mi (4.5 km) from Saint Francis Healthcare System.
Comfort Suites Jackson-Cape Girardeau Facility and Service
Enjoy recreational amenities such as an indoor pool and a fitness center. Additional amenities at this hotel include complimentary wireless internet access, gift shops/newsstands, and a television in a common area.
Comfort Suites Jackson-Cape Girardeau Rooms
Make yourself at home in one of the 64 guestrooms featuring refrigerators and flat-screen televisions. Complimentary wireless internet access keeps you connected, and cable programming is available for your entertainment. Bathrooms have complimentary toiletries and hair dryers. Conveniences include desks and complimentary weekday newspapers, as well as phones with free local calls.
Restaurant and Cafe
A complimentary buffet breakfast is included.
See detailsWith a stay at Comfort Suites Jackson-Cape Girardeau, you'll be centrally located in Jackson, within a 15-minute drive of Shawnee National Forest and Mississippi River. This hotel is 1.5 mi (2.5 km) from Cape Girardeau Conservation Nature Center and 2.8 mi (4.5 km) from Saint Francis Healthcare System.
Comfort Suites Jackson-Cape Girardeau Facility and Service
Enjoy recreational amenities such as an indoor pool and a fitness center. Additional amenities at this hotel include complimentary wireless internet access, gift shops/newsstands, and a television in a common area.
Comfort Suites Jackson-Cape Girardeau Rooms
Make yourself at home in one of the 64 guestrooms featuring refrigerators and flat-screen televisions. Complimentary wireless internet access keeps you connected, and cable programming is available for your entertainment. Bathrooms have complimentary toiletries and hair dryers. Conveniences include desks and complimentary weekday newspapers, as well as phones with free local calls.
Restaurant and Cafe
A complimentary buffet breakfast is included.
Comfort Suites Jackson-Cape Girardeau
The well-being of guests is top of mind at Choice-branded hotels. Guests may experience a variety of new, improved cleanliness protocols and products. Get more of the space you need to spread out, relax or work at the smoke-free Comfort Suites Jackson-Cape Girardeau hotel in Jackson, MO off Interstate 55. Nearby destinations include Southeast Missouri State University, Shawnee Park Sports Complex, Riverfront Park of Cape Girardeau, Trail of Tears State Park and Southeast Missouri Hospital. Enjoy amenities like free hot breakfast, free WiFi, fitness center, business center and indoor heated pool. Spacious suites include HDTV, refrigerator, microwave, hair dryer, sofa sleeper and recharge device. Also, earn rewards including free nights and gift cards with our Choice Privileges Rewards program.
See detailsTown House Inn
Town House Inn Location
Located in Jackson, Town House Inn is within a 15-minute drive of Shawnee National Forest and Mississippi River. This motel is 1.3 mi (2 km) from Litz Park and 4.7 mi (7.5 km) from Cape Girardeau Conservation Nature Center.
Town House Inn Rooms
Make yourself at home in one of the 21 air-conditioned rooms featuring kitchenettes with refrigerators and ovens. Flat-screen televisions with cable programming provide entertainment, while complimentary wireless internet access keeps you connected. Conveniences include microwaves and coffee/tea makers, and housekeeping is provided daily.
See detailsLocated in Jackson, Town House Inn is within a 15-minute drive of Shawnee National Forest and Mississippi River. This motel is 1.3 mi (2 km) from Litz Park and 4.7 mi (7.5 km) from Cape Girardeau Conservation Nature Center.
Town House Inn Rooms
Make yourself at home in one of the 21 air-conditioned rooms featuring kitchenettes with refrigerators and ovens. Flat-screen televisions with cable programming provide entertainment, while complimentary wireless internet access keeps you connected. Conveniences include microwaves and coffee/tea makers, and housekeeping is provided daily.
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau Location
When you stay at La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau in Jackson, you'll be in the business district, within a 15-minute drive of Shawnee National Forest and Mississippi River. This hotel is 1.5 mi (2.3 km) from Cape Girardeau Conservation Nature Center and 2.7 mi (4.4 km) from Saint Francis Healthcare System.
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau Facility and Service
Don't miss out on recreational opportunities including an indoor pool and a 24-hour fitness center. This hotel also features complimentary wireless internet access, a banquet hall, and a vending machine.
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau Rooms
Make yourself at home in one of the 80 air-conditioned rooms featuring refrigerators and microwaves. 49-inch LED televisions with cable programming provide entertainment, while complimentary wireless internet access keeps you connected. Bathrooms feature bathtubs or showers, complimentary toiletries, and hair dryers. Conveniences include desks and coffee/tea makers, as well as phones with free local calls.
Restaurant and Cafe
Grab a bite from the snack bar/deli, or stay in and take advantage of the hotel's room service (during limited hours). A complimentary self-serve breakfast is served on weekdays from 6:00 AM to 9:00 AM and on weekends from 6:00 AM to 10:00 AM.
See detailsWhen you stay at La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau in Jackson, you'll be in the business district, within a 15-minute drive of Shawnee National Forest and Mississippi River. This hotel is 1.5 mi (2.3 km) from Cape Girardeau Conservation Nature Center and 2.7 mi (4.4 km) from Saint Francis Healthcare System.
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau Facility and Service
Don't miss out on recreational opportunities including an indoor pool and a 24-hour fitness center. This hotel also features complimentary wireless internet access, a banquet hall, and a vending machine.
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau Rooms
Make yourself at home in one of the 80 air-conditioned rooms featuring refrigerators and microwaves. 49-inch LED televisions with cable programming provide entertainment, while complimentary wireless internet access keeps you connected. Bathrooms feature bathtubs or showers, complimentary toiletries, and hair dryers. Conveniences include desks and coffee/tea makers, as well as phones with free local calls.
Restaurant and Cafe
Grab a bite from the snack bar/deli, or stay in and take advantage of the hotel's room service (during limited hours). A complimentary self-serve breakfast is served on weekdays from 6:00 AM to 9:00 AM and on weekends from 6:00 AM to 10:00 AM.
“Worth it”
Quality Inn Cape Girardeau
The well-being of guests is top of mind at Choice-branded hotels. Guests may experience a variety of new, improved cleanliness protocols and products. Get more for your money at the Quality Inn and Suites hotel in Vacaville, CA. Our convenient location near I-80, between Sacramento and San Francisco, makes this hotel your ideal lodging destination when traveling for business or pleasure. For your convenience, our business center offers access to copy and fax services. Guest laundry facilities are available, too. We also have ample parking for buses and trucks. Additional must-have amenities include free WiFi, grab and go breakfast, outdoor pool and a spa. We invite you to relax in your guest room, which features a refrigerator, microwave, coffee maker, hair dryer, iron and ironing board.
See detailsCandlewood Suites CAPE GIRARDEAU
A historic college town in southeastern Missouri, Cape Girardeau is bordered on the east by the mighty Mississippi River. The only extended stay in the area, the Candlewood Suites® Cape Girardeau hotel's spacious suites offer travelers a room to work and a place to relax, as well as convenient access to the best attractions in Cape Girardeau, MO.
The newly renovated hotel's location is just off I-55 in southeastern Missouri, convenient to St. Francis Hospital and Landmark Hospital. Convenient to the regional airport. Business travelers appreciate such amenities as free high-speed, wireless Internet access and a 24-hour Business Center with printing capabilities.
Cape Girardeau location is also exciting for leisure travelers. Nearby Southeast Missouri State University provides year-round opportunities for sporting events and cultural activities. Nature lovers enjoy the area's beautiful vistas and numerous parks, including the Trail of Tears State Park. The Shawnee Park Sports Complex is also near this hotel's Cape Girardeau location.
Guests can expect convenient amenities at this hotel, including a free guest laundry facility and a 24-hour Fitness Center. The outdoor Gazebo Grill area is the perfect place to gather with friends and family, and the indoor pool is the perfect place to cool off after a long day. Visit historic Cape Girardeau, MO and meet the hotel's friendly staff.
Auburn Place Hotel & Suites Cape Girardeau
Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference Center Location
When you stay at Drury Plaza Hotel Cape Girardeau Conference Center in Cape Girardeau, you'll be connected to the convention center, within a 10-minute drive of Shawnee National Forest and Mississippi River. This hotel is 0.7 mi (1.1 km) from Saint Francis Medical Center and 2.2 mi (3.5 km) from Saint Francis Healthcare System.
Drury Plaza Hotel Cape Girardeau Conference Center Facility and Service
Be sure to enjoy recreational amenities, including an indoor pool, a hot tub, and a fitness center. This hotel also features complimentary wireless internet access and a banquet hall.
Drury Plaza Hotel Cape Girardeau Conference Center Rooms
Make yourself at home in one of the 168 guestrooms featuring refrigerators and microwaves. 43-inch LCD televisions with cable programming provide entertainment, while complimentary wireless internet access keeps you connected. Bathrooms have shower/tub combinations and hair dryers. Conveniences include desks and separate sitting areas, as well as phones with free local calls.
Restaurant and Cafe
Enjoy a satisfying meal at The Southerner serving guests of Drury Plaza Hotel Cape Girardeau Conference Center. Mingle with other guests at the complimentary reception, held daily. A complimentary buffet breakfast is served on weekdays from 6:00 AM to 9:00 AM and on weekends from 7:00 AM to 10:00 AM.
See detailsWhen you stay at Drury Plaza Hotel Cape Girardeau Conference Center in Cape Girardeau, you'll be connected to the convention center, within a 10-minute drive of Shawnee National Forest and Mississippi River. This hotel is 0.7 mi (1.1 km) from Saint Francis Medical Center and 2.2 mi (3.5 km) from Saint Francis Healthcare System.
Drury Plaza Hotel Cape Girardeau Conference Center Facility and Service
Be sure to enjoy recreational amenities, including an indoor pool, a hot tub, and a fitness center. This hotel also features complimentary wireless internet access and a banquet hall.
Drury Plaza Hotel Cape Girardeau Conference Center Rooms
Make yourself at home in one of the 168 guestrooms featuring refrigerators and microwaves. 43-inch LCD televisions with cable programming provide entertainment, while complimentary wireless internet access keeps you connected. Bathrooms have shower/tub combinations and hair dryers. Conveniences include desks and separate sitting areas, as well as phones with free local calls.
Restaurant and Cafe
Enjoy a satisfying meal at The Southerner serving guests of Drury Plaza Hotel Cape Girardeau Conference Center. Mingle with other guests at the complimentary reception, held daily. A complimentary buffet breakfast is served on weekdays from 6:00 AM to 9:00 AM and on weekends from 7:00 AM to 10:00 AM.
“Great deal”
The Riverview
The Riverview Location
When you stay at The Riverview in Cape Girardeau, you'll be in the entertainment district, within a 15-minute walk of Mississippi River and Shawnee National Forest. This casino hotel is 0.1 mi (0.1 km) from Century Casino & Hotel Cape Girardeau and 0.1 mi (0.2 km) from Riverfront Park.
The Riverview Facility and Service
Take advantage of recreation opportunities such as a casino, or other amenities including complimentary wireless internet access and gift shops/newsstands. Additional features at this hotel include wedding services, a television in a common area, and a vending machine.
The Riverview Rooms
Make yourself at home in one of the 69 air-conditioned rooms featuring LED televisions. Your pillowtop bed comes with premium bedding. Complimentary wireless internet access keeps you connected, and satellite programming is available for your entertainment. Bathrooms have showers and hair dryers.
Restaurant and Cafe
Enjoy American cuisine at Beacon 53, one of the hotel's many dining establishments, which include 2 restaurants and a coffee shop/cafe. Need to unwind? Take a break with a tasty beverage at one of the 2 bars/lounges. To-go breakfasts are available daily from 5:00 AM to 1:00 PM for a fee.
See detailsWhen you stay at The Riverview in Cape Girardeau, you'll be in the entertainment district, within a 15-minute walk of Mississippi River and Shawnee National Forest. This casino hotel is 0.1 mi (0.1 km) from Century Casino & Hotel Cape Girardeau and 0.1 mi (0.2 km) from Riverfront Park.
The Riverview Facility and Service
Take advantage of recreation opportunities such as a casino, or other amenities including complimentary wireless internet access and gift shops/newsstands. Additional features at this hotel include wedding services, a television in a common area, and a vending machine.
The Riverview Rooms
Make yourself at home in one of the 69 air-conditioned rooms featuring LED televisions. Your pillowtop bed comes with premium bedding. Complimentary wireless internet access keeps you connected, and satellite programming is available for your entertainment. Bathrooms have showers and hair dryers.
Restaurant and Cafe
Enjoy American cuisine at Beacon 53, one of the hotel's many dining establishments, which include 2 restaurants and a coffee shop/cafe. Need to unwind? Take a break with a tasty beverage at one of the 2 bars/lounges. To-go breakfasts are available daily from 5:00 AM to 1:00 PM for a fee.
“Great deal”
Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau West Location
Located in Cape Girardeau, Pear Tree Inn Cape Girardeau West is in a rural location, a 3-minute drive from Saint Francis Medical Center and 5 minutes from Saint Francis Healthcare System. This hotel is 4.5 mi (7.2 km) from Shawnee National Forest and 4.8 mi (7.8 km) from Mississippi River.
Pear Tree Inn Cape Girardeau West Facility and Service
Make use of convenient amenities, which include complimentary wireless internet access and a television in a common area.
Pear Tree Inn Cape Girardeau West Rooms
Make yourself at home in one of the 81 guestrooms featuring refrigerators and LCD televisions. Complimentary wireless internet access is available to keep you connected. Bathrooms have shower/tub combinations and hair dryers. Conveniences include desks and microwaves, as well as phones with free local calls.
Restaurant and Cafe
A complimentary buffet breakfast is served on weekdays from 6:00 AM to 9:00 AM.
See detailsLocated in Cape Girardeau, Pear Tree Inn Cape Girardeau West is in a rural location, a 3-minute drive from Saint Francis Medical Center and 5 minutes from Saint Francis Healthcare System. This hotel is 4.5 mi (7.2 km) from Shawnee National Forest and 4.8 mi (7.8 km) from Mississippi River.
Pear Tree Inn Cape Girardeau West Facility and Service
Make use of convenient amenities, which include complimentary wireless internet access and a television in a common area.
Pear Tree Inn Cape Girardeau West Rooms
Make yourself at home in one of the 81 guestrooms featuring refrigerators and LCD televisions. Complimentary wireless internet access is available to keep you connected. Bathrooms have shower/tub combinations and hair dryers. Conveniences include desks and microwaves, as well as phones with free local calls.
Restaurant and Cafe
A complimentary buffet breakfast is served on weekdays from 6:00 AM to 9:00 AM.
“Great deal”
Jackson Town House Inn
Town House Inn
Cheap hotel Promo in Cape Girardeau Today
Quality Inn Cape Girardeau North
Quality Inn Cape Girardeau North Location
With a stay at Quality Inn Cape Girardeau North in Cape Girardeau, you'll be within a 10-minute drive of Shawnee National Forest and Mississippi River. This hotel is 0.6 mi (1 km) from Saint Francis Healthcare System and 0.9 mi (1.4 km) from Cape Splash Family Aquatic Center.
Quality Inn Cape Girardeau North Facility and Service
Take advantage of recreation opportunities such as an outdoor pool, or other amenities including complimentary wireless internet access and a television in a common area.
Quality Inn Cape Girardeau North Rooms
Make yourself at home in one of the 49 air-conditioned guestrooms. Your memory foam bed comes with down comforters and Egyptian cotton sheets. Complimentary wireless internet access keeps you connected, and cable programming is available for your entertainment. Bathrooms feature shower/tub combinations, complimentary toiletries, and hair dryers.
Restaurant and Cafe
A complimentary continental breakfast is served on weekdays from 6:00 AM to 9:00 AM and on weekends from 7:00 AM to 10:00 AM.
See detailsWith a stay at Quality Inn Cape Girardeau North in Cape Girardeau, you'll be within a 10-minute drive of Shawnee National Forest and Mississippi River. This hotel is 0.6 mi (1 km) from Saint Francis Healthcare System and 0.9 mi (1.4 km) from Cape Splash Family Aquatic Center.
Quality Inn Cape Girardeau North Facility and Service
Take advantage of recreation opportunities such as an outdoor pool, or other amenities including complimentary wireless internet access and a television in a common area.
Quality Inn Cape Girardeau North Rooms
Make yourself at home in one of the 49 air-conditioned guestrooms. Your memory foam bed comes with down comforters and Egyptian cotton sheets. Complimentary wireless internet access keeps you connected, and cable programming is available for your entertainment. Bathrooms feature shower/tub combinations, complimentary toiletries, and hair dryers.
Restaurant and Cafe
A complimentary continental breakfast is served on weekdays from 6:00 AM to 9:00 AM and on weekends from 7:00 AM to 10:00 AM.
Comfort Suites Jackson-Cape Girardeau
Comfort Suites Jackson-Cape Girardeau Location
With a stay at Comfort Suites Jackson-Cape Girardeau, you'll be centrally located in Jackson, within a 15-minute drive of Shawnee National Forest and Mississippi River. This hotel is 1.5 mi (2.5 km) from Cape Girardeau Conservation Nature Center and 2.8 mi (4.5 km) from Saint Francis Healthcare System.
Comfort Suites Jackson-Cape Girardeau Facility and Service
Enjoy recreational amenities such as an indoor pool and a fitness center. Additional amenities at this hotel include complimentary wireless internet access, gift shops/newsstands, and a television in a common area.
Comfort Suites Jackson-Cape Girardeau Rooms
Make yourself at home in one of the 64 guestrooms featuring refrigerators and flat-screen televisions. Complimentary wireless internet access keeps you connected, and cable programming is available for your entertainment. Bathrooms have complimentary toiletries and hair dryers. Conveniences include desks and complimentary weekday newspapers, as well as phones with free local calls.
Restaurant and Cafe
A complimentary buffet breakfast is included.
See detailsWith a stay at Comfort Suites Jackson-Cape Girardeau, you'll be centrally located in Jackson, within a 15-minute drive of Shawnee National Forest and Mississippi River. This hotel is 1.5 mi (2.5 km) from Cape Girardeau Conservation Nature Center and 2.8 mi (4.5 km) from Saint Francis Healthcare System.
Comfort Suites Jackson-Cape Girardeau Facility and Service
Enjoy recreational amenities such as an indoor pool and a fitness center. Additional amenities at this hotel include complimentary wireless internet access, gift shops/newsstands, and a television in a common area.
Comfort Suites Jackson-Cape Girardeau Rooms
Make yourself at home in one of the 64 guestrooms featuring refrigerators and flat-screen televisions. Complimentary wireless internet access keeps you connected, and cable programming is available for your entertainment. Bathrooms have complimentary toiletries and hair dryers. Conveniences include desks and complimentary weekday newspapers, as well as phones with free local calls.
Restaurant and Cafe
A complimentary buffet breakfast is included.
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
“Worth it”
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau Location
When you stay at La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau in Jackson, you'll be in the business district, within a 15-minute drive of Shawnee National Forest and Mississippi River. This hotel is 1.5 mi (2.3 km) from Cape Girardeau Conservation Nature Center and 2.7 mi (4.4 km) from Saint Francis Healthcare System.
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau Facility and Service
Don't miss out on recreational opportunities including an indoor pool and a 24-hour fitness center. This hotel also features complimentary wireless internet access, a banquet hall, and a vending machine.
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau Rooms
Make yourself at home in one of the 80 air-conditioned rooms featuring refrigerators and microwaves. 49-inch LED televisions with cable programming provide entertainment, while complimentary wireless internet access keeps you connected. Bathrooms feature bathtubs or showers, complimentary toiletries, and hair dryers. Conveniences include desks and coffee/tea makers, as well as phones with free local calls.
Restaurant and Cafe
Grab a bite from the snack bar/deli, or stay in and take advantage of the hotel's room service (during limited hours). A complimentary self-serve breakfast is served on weekdays from 6:00 AM to 9:00 AM and on weekends from 6:00 AM to 10:00 AM.
See detailsWhen you stay at La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau in Jackson, you'll be in the business district, within a 15-minute drive of Shawnee National Forest and Mississippi River. This hotel is 1.5 mi (2.3 km) from Cape Girardeau Conservation Nature Center and 2.7 mi (4.4 km) from Saint Francis Healthcare System.
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau Facility and Service
Don't miss out on recreational opportunities including an indoor pool and a 24-hour fitness center. This hotel also features complimentary wireless internet access, a banquet hall, and a vending machine.
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau Rooms
Make yourself at home in one of the 80 air-conditioned rooms featuring refrigerators and microwaves. 49-inch LED televisions with cable programming provide entertainment, while complimentary wireless internet access keeps you connected. Bathrooms feature bathtubs or showers, complimentary toiletries, and hair dryers. Conveniences include desks and coffee/tea makers, as well as phones with free local calls.
Restaurant and Cafe
Grab a bite from the snack bar/deli, or stay in and take advantage of the hotel's room service (during limited hours). A complimentary self-serve breakfast is served on weekdays from 6:00 AM to 9:00 AM and on weekends from 6:00 AM to 10:00 AM.
Pear Tree Inn Cape Girardeau West
“Great deal”
Pear Tree Inn Cape Girardeau West Location
Located in Cape Girardeau, Pear Tree Inn Cape Girardeau West is in a rural location, a 3-minute drive from Saint Francis Medical Center and 5 minutes from Saint Francis Healthcare System. This hotel is 4.5 mi (7.2 km) from Shawnee National Forest and 4.8 mi (7.8 km) from Mississippi River.
Pear Tree Inn Cape Girardeau West Facility and Service
Make use of convenient amenities, which include complimentary wireless internet access and a television in a common area.
Pear Tree Inn Cape Girardeau West Rooms
Make yourself at home in one of the 81 guestrooms featuring refrigerators and LCD televisions. Complimentary wireless internet access is available to keep you connected. Bathrooms have shower/tub combinations and hair dryers. Conveniences include desks and microwaves, as well as phones with free local calls.
Restaurant and Cafe
A complimentary buffet breakfast is served on weekdays from 6:00 AM to 9:00 AM.
See detailsLocated in Cape Girardeau, Pear Tree Inn Cape Girardeau West is in a rural location, a 3-minute drive from Saint Francis Medical Center and 5 minutes from Saint Francis Healthcare System. This hotel is 4.5 mi (7.2 km) from Shawnee National Forest and 4.8 mi (7.8 km) from Mississippi River.
Pear Tree Inn Cape Girardeau West Facility and Service
Make use of convenient amenities, which include complimentary wireless internet access and a television in a common area.
Pear Tree Inn Cape Girardeau West Rooms
Make yourself at home in one of the 81 guestrooms featuring refrigerators and LCD televisions. Complimentary wireless internet access is available to keep you connected. Bathrooms have shower/tub combinations and hair dryers. Conveniences include desks and microwaves, as well as phones with free local calls.
Restaurant and Cafe
A complimentary buffet breakfast is served on weekdays from 6:00 AM to 9:00 AM.
Candlewood Suites CAPE GIRARDEAU
A historic college town in southeastern Missouri, Cape Girardeau is bordered on the east by the mighty Mississippi River. The only extended stay in the area, the Candlewood Suites® Cape Girardeau hotel's spacious suites offer travelers a room to work and a place to relax, as well as convenient access to the best attractions in Cape Girardeau, MO.
The newly renovated hotel's location is just off I-55 in southeastern Missouri, convenient to St. Francis Hospital and Landmark Hospital. Convenient to the regional airport. Business travelers appreciate such amenities as free high-speed, wireless Internet access and a 24-hour Business Center with printing capabilities.
Cape Girardeau location is also exciting for leisure travelers. Nearby Southeast Missouri State University provides year-round opportunities for sporting events and cultural activities. Nature lovers enjoy the area's beautiful vistas and numerous parks, including the Trail of Tears State Park. The Shawnee Park Sports Complex is also near this hotel's Cape Girardeau location.
Guests can expect convenient amenities at this hotel, including a free guest laundry facility and a 24-hour Fitness Center. The outdoor Gazebo Grill area is the perfect place to gather with friends and family, and the indoor pool is the perfect place to cool off after a long day. Visit historic Cape Girardeau, MO and meet the hotel's friendly staff.
Holiday Inn Express & Suites CAPE GIRARDEAU I-55 by IHG
“Great deal”
Welcome to Our Cape Girardeau Hotel. Just off I- 55 at exit 96, the Holiday Inn Express Hotel & Suites Cape Girardeau I-55 offers hotel guests 102 spacious, contemporary suites. Vacation and business guests alike choose these accommodations for a comfortable and convenient stay. Our Cape Girardeau, Missouri hotel is just minutes from Southeast Missouri State University, where guests are encouraged to cheer on the Redhawks in football and basketball. We're also only 10 miles from Trail of Tears State Park, so families can enjoy picnics, hiking, biking and fishing. Be sure to stop by our Old Downtown area where you will not only enjoy a variety of shops and restaurants, but you can enjoy the great view of the Mississippi River. Business travelers appreciate our Cape Girardeau, Missouri hotel's convenient location close to St. Francis Hospital, Southeast Missouri Hospital, Doctors Park, the Show Me Center, Procter & Gamble, Mondi, Shawnee Park and Biokyowa. We provide two spacious meeting rooms, as well, which feature A/V equipment ideal for business functions or special events. With the help of our professional staff, your event can be a success. At our Girardeau hotel, we know it's the extra perks that make your stay unforgettable. We provide an indoor pool and well-equipped fitness center to help you relax and unwind. Be sure to stop by our breakfast bar each morning, too, for biscuits, eggs, fruit and our signature cinnamon rolls. We look forward to your next visit!
See details
Tru by Hilton Cape Girardeau
From our daily free hot breakfast to our nightly cookie hour, Tru Cape Girardeau makes you feel at home. Located just off Interstate 55 at exit 99, we are conveniently located near the Cape Girardeau Sportsplex, Southeast Missouri State University, and the Conservation Nature Center. This beautiful hotel offers all the amenities you need while traveling. Start your day with a quick workout in the fitness center or with some laps in the heated indoor pool. Sit down to a free, hot breakfast served daily with items including fresh-baked waffles, eggs, biscuits and gravy, and rotating options. Stay connected to the office with free Wi-Fi in every room or work from one of our quaint business nooks located in the lobby. End your day at our nightly cookie hour with warm cookies, cold milk, and friendly team members available for your questions or concerns.
See detailsThe Riverview
“Great deal”
The Riverview Location
When you stay at The Riverview in Cape Girardeau, you'll be in the entertainment district, within a 15-minute walk of Mississippi River and Shawnee National Forest. This casino hotel is 0.1 mi (0.1 km) from Century Casino & Hotel Cape Girardeau and 0.1 mi (0.2 km) from Riverfront Park.
The Riverview Facility and Service
Take advantage of recreation opportunities such as a casino, or other amenities including complimentary wireless internet access and gift shops/newsstands. Additional features at this hotel include wedding services, a television in a common area, and a vending machine.
The Riverview Rooms
Make yourself at home in one of the 69 air-conditioned rooms featuring LED televisions. Your pillowtop bed comes with premium bedding. Complimentary wireless internet access keeps you connected, and satellite programming is available for your entertainment. Bathrooms have showers and hair dryers.
Restaurant and Cafe
Enjoy American cuisine at Beacon 53, one of the hotel's many dining establishments, which include 2 restaurants and a coffee shop/cafe. Need to unwind? Take a break with a tasty beverage at one of the 2 bars/lounges. To-go breakfasts are available daily from 5:00 AM to 1:00 PM for a fee.
See detailsWhen you stay at The Riverview in Cape Girardeau, you'll be in the entertainment district, within a 15-minute walk of Mississippi River and Shawnee National Forest. This casino hotel is 0.1 mi (0.1 km) from Century Casino & Hotel Cape Girardeau and 0.1 mi (0.2 km) from Riverfront Park.
The Riverview Facility and Service
Take advantage of recreation opportunities such as a casino, or other amenities including complimentary wireless internet access and gift shops/newsstands. Additional features at this hotel include wedding services, a television in a common area, and a vending machine.
The Riverview Rooms
Make yourself at home in one of the 69 air-conditioned rooms featuring LED televisions. Your pillowtop bed comes with premium bedding. Complimentary wireless internet access keeps you connected, and satellite programming is available for your entertainment. Bathrooms have showers and hair dryers.
Restaurant and Cafe
Enjoy American cuisine at Beacon 53, one of the hotel's many dining establishments, which include 2 restaurants and a coffee shop/cafe. Need to unwind? Take a break with a tasty beverage at one of the 2 bars/lounges. To-go breakfasts are available daily from 5:00 AM to 1:00 PM for a fee.
Drury Inn & Suites Jackson MO
“Great deal”
Drury Inn & Suites Jackson MO Location
With a stay at Drury Inn & Suites Jackson MO, you'll be centrally located in Jackson, within a 10-minute drive of Cape Girardeau Conservation Nature Center and Saint Francis Healthcare System. This hotel is 10.2 mi (16.5 km) from Mississippi River and 10.4 mi (16.7 km) from Shawnee National Forest.
Drury Inn & Suites Jackson MO Facility and Service
Take advantage of recreational opportunities offered, including an indoor pool, a hot tub, and a fitness center. Additional features at this hotel include complimentary wireless internet access, a television in a common area, and a banquet hall.
Drury Inn & Suites Jackson MO Rooms
Make yourself at home in one of the 80 guestrooms featuring refrigerators and microwaves. LCD televisions with cable programming provide entertainment, while complimentary wireless internet access keeps you connected. Private bathrooms with shower/tub combinations feature complimentary toiletries and hair dryers. Conveniences include desks and separate sitting areas, as well as phones with free local calls.
Restaurant and Cafe
Meet other guests and eat at the complimentary reception. A complimentary buffet breakfast is served on weekdays from 6:00 AM to 9:00 AM and on weekends from 7:00 AM to 10:00 AM.
See detailsWith a stay at Drury Inn & Suites Jackson MO, you'll be centrally located in Jackson, within a 10-minute drive of Cape Girardeau Conservation Nature Center and Saint Francis Healthcare System. This hotel is 10.2 mi (16.5 km) from Mississippi River and 10.4 mi (16.7 km) from Shawnee National Forest.
Drury Inn & Suites Jackson MO Facility and Service
Take advantage of recreational opportunities offered, including an indoor pool, a hot tub, and a fitness center. Additional features at this hotel include complimentary wireless internet access, a television in a common area, and a banquet hall.
Drury Inn & Suites Jackson MO Rooms
Make yourself at home in one of the 80 guestrooms featuring refrigerators and microwaves. LCD televisions with cable programming provide entertainment, while complimentary wireless internet access keeps you connected. Private bathrooms with shower/tub combinations feature complimentary toiletries and hair dryers. Conveniences include desks and separate sitting areas, as well as phones with free local calls.
Restaurant and Cafe
Meet other guests and eat at the complimentary reception. A complimentary buffet breakfast is served on weekdays from 6:00 AM to 9:00 AM and on weekends from 7:00 AM to 10:00 AM.
Drury Plaza Hotel Cape Girardeau Conference Center
“Great deal”
Drury Plaza Hotel Cape Girardeau Conference Center Location
When you stay at Drury Plaza Hotel Cape Girardeau Conference Center in Cape Girardeau, you'll be connected to the convention center, within a 10-minute drive of Shawnee National Forest and Mississippi River. This hotel is 0.7 mi (1.1 km) from Saint Francis Medical Center and 2.2 mi (3.5 km) from Saint Francis Healthcare System.
Drury Plaza Hotel Cape Girardeau Conference Center Facility and Service
Be sure to enjoy recreational amenities, including an indoor pool, a hot tub, and a fitness center. This hotel also features complimentary wireless internet access and a banquet hall.
Drury Plaza Hotel Cape Girardeau Conference Center Rooms
Make yourself at home in one of the 168 guestrooms featuring refrigerators and microwaves. 43-inch LCD televisions with cable programming provide entertainment, while complimentary wireless internet access keeps you connected. Bathrooms have shower/tub combinations and hair dryers. Conveniences include desks and separate sitting areas, as well as phones with free local calls.
Restaurant and Cafe
Enjoy a satisfying meal at The Southerner serving guests of Drury Plaza Hotel Cape Girardeau Conference Center. Mingle with other guests at the complimentary reception, held daily. A complimentary buffet breakfast is served on weekdays from 6:00 AM to 9:00 AM and on weekends from 7:00 AM to 10:00 AM.
See detailsWhen you stay at Drury Plaza Hotel Cape Girardeau Conference Center in Cape Girardeau, you'll be connected to the convention center, within a 10-minute drive of Shawnee National Forest and Mississippi River. This hotel is 0.7 mi (1.1 km) from Saint Francis Medical Center and 2.2 mi (3.5 km) from Saint Francis Healthcare System.
Drury Plaza Hotel Cape Girardeau Conference Center Facility and Service
Be sure to enjoy recreational amenities, including an indoor pool, a hot tub, and a fitness center. This hotel also features complimentary wireless internet access and a banquet hall.
Drury Plaza Hotel Cape Girardeau Conference Center Rooms
Make yourself at home in one of the 168 guestrooms featuring refrigerators and microwaves. 43-inch LCD televisions with cable programming provide entertainment, while complimentary wireless internet access keeps you connected. Bathrooms have shower/tub combinations and hair dryers. Conveniences include desks and separate sitting areas, as well as phones with free local calls.
Restaurant and Cafe
Enjoy a satisfying meal at The Southerner serving guests of Drury Plaza Hotel Cape Girardeau Conference Center. Mingle with other guests at the complimentary reception, held daily. A complimentary buffet breakfast is served on weekdays from 6:00 AM to 9:00 AM and on weekends from 7:00 AM to 10:00 AM.
Tru By Hilton Cape Girardeau
Tru By Hilton Cape Girardeau Location
With a stay at Tru By Hilton Cape Girardeau in Cape Girardeau, you'll be within a 10-minute drive of Shawnee National Forest and Mississippi River. This hotel is 0.7 mi (1.1 km) from Cape Girardeau Conservation Nature Center and 2 mi (3.2 km) from Saint Francis Healthcare System.
Tru By Hilton Cape Girardeau Facility and Service
Take advantage of recreation opportunities including an indoor pool and a fitness center.
Tru By Hilton Cape Girardeau Rooms
Make yourself at home in one of the air-conditioned guestrooms. Cable television is provided for your entertainment. Bathrooms have complimentary toiletries and hair dryers.
Restaurant and Cafe
For your convenience, a complimentary breakfast is served daily.
See detailsWith a stay at Tru By Hilton Cape Girardeau in Cape Girardeau, you'll be within a 10-minute drive of Shawnee National Forest and Mississippi River. This hotel is 0.7 mi (1.1 km) from Cape Girardeau Conservation Nature Center and 2 mi (3.2 km) from Saint Francis Healthcare System.
Tru By Hilton Cape Girardeau Facility and Service
Take advantage of recreation opportunities including an indoor pool and a fitness center.
Tru By Hilton Cape Girardeau Rooms
Make yourself at home in one of the air-conditioned guestrooms. Cable television is provided for your entertainment. Bathrooms have complimentary toiletries and hair dryers.
Restaurant and Cafe
For your convenience, a complimentary breakfast is served daily.
Drury Inn & Suites Cape Girardeau
“Great deal”
Drury Inn & Suites Cape Girardeau Location
With a stay at Drury Inn & Suites Cape Girardeau, you'll be centrally located in Cape Girardeau, within a 10-minute drive of Shawnee National Forest and Mississippi River. This hotel is 1.2 mi (2 km) from Saint Francis Medical Center and 2.7 mi (4.3 km) from Saint Francis Healthcare System.
Drury Inn & Suites Cape Girardeau Facility and Service
Be sure to enjoy recreational amenities, including an indoor pool, a hot tub, and a fitness center. Additional features at this hotel include complimentary wireless internet access, a television in a common area, and a banquet hall.
Drury Inn & Suites Cape Girardeau Rooms
Make yourself at home in one of the 87 guestrooms featuring refrigerators and LCD televisions. Complimentary wireless internet access keeps you connected, and cable programming is available for your entertainment. Private bathrooms with shower/tub combinations feature complimentary toiletries and hair dryers. Conveniences include desks and separate sitting areas, as well as phones with free local calls.
Restaurant and Cafe
Meet other guests and eat at the complimentary reception. A complimentary buffet breakfast is served on weekdays from 6:00 AM to 9:00 AM and on weekends from 7:00 AM to 10:00 AM.
Important Information
The following facilities or services will be unavailable from August 10 2026 to August 21 2026 (dates subject to change):
See detailsWith a stay at Drury Inn & Suites Cape Girardeau, you'll be centrally located in Cape Girardeau, within a 10-minute drive of Shawnee National Forest and Mississippi River. This hotel is 1.2 mi (2 km) from Saint Francis Medical Center and 2.7 mi (4.3 km) from Saint Francis Healthcare System.
Drury Inn & Suites Cape Girardeau Facility and Service
Be sure to enjoy recreational amenities, including an indoor pool, a hot tub, and a fitness center. Additional features at this hotel include complimentary wireless internet access, a television in a common area, and a banquet hall.
Drury Inn & Suites Cape Girardeau Rooms
Make yourself at home in one of the 87 guestrooms featuring refrigerators and LCD televisions. Complimentary wireless internet access keeps you connected, and cable programming is available for your entertainment. Private bathrooms with shower/tub combinations feature complimentary toiletries and hair dryers. Conveniences include desks and separate sitting areas, as well as phones with free local calls.
Restaurant and Cafe
Meet other guests and eat at the complimentary reception. A complimentary buffet breakfast is served on weekdays from 6:00 AM to 9:00 AM and on weekends from 7:00 AM to 10:00 AM.
Important Information
The following facilities or services will be unavailable from August 10 2026 to August 21 2026 (dates subject to change):
- Hot tub
- Swimming pool
Hampton Inn Cape Girardeau I 55 East
“Great deal”
Hampton Inn Cape Girardeau I 55 East Location
With a stay at Hampton Inn Cape Girardeau I 55 East in Cape Girardeau, you'll be within a 10-minute drive of Shawnee National Forest and Mississippi River. This hotel is 0.5 mi (0.8 km) from Saint Francis Medical Center and 2.3 mi (3.7 km) from Saint Francis Healthcare System.
Hampton Inn Cape Girardeau I 55 East Facility and Service
Don't miss out on recreational opportunities including an indoor pool and a fitness center. Additional features at this hotel include complimentary wireless internet access, a picnic area, and a banquet hall.
Hampton Inn Cape Girardeau I 55 East Rooms
Make yourself at home in one of the 86 guestrooms featuring refrigerators and flat-screen televisions. Complimentary wired and wireless internet access keeps you connected, and cable programming provides entertainment. Private bathrooms with shower/tub combinations feature complimentary toiletries and hair dryers. Conveniences include safes and desks, as well as phones with free local calls.
Restaurant and Cafe
Grab a bite from the snack bar/deli serving guests of Hampton Inn Cape Girardeau I 55 East. A complimentary buffet breakfast is served daily from 6 AM to 10 AM.
See detailsWith a stay at Hampton Inn Cape Girardeau I 55 East in Cape Girardeau, you'll be within a 10-minute drive of Shawnee National Forest and Mississippi River. This hotel is 0.5 mi (0.8 km) from Saint Francis Medical Center and 2.3 mi (3.7 km) from Saint Francis Healthcare System.
Hampton Inn Cape Girardeau I 55 East Facility and Service
Don't miss out on recreational opportunities including an indoor pool and a fitness center. Additional features at this hotel include complimentary wireless internet access, a picnic area, and a banquet hall.
Hampton Inn Cape Girardeau I 55 East Rooms
Make yourself at home in one of the 86 guestrooms featuring refrigerators and flat-screen televisions. Complimentary wired and wireless internet access keeps you connected, and cable programming provides entertainment. Private bathrooms with shower/tub combinations feature complimentary toiletries and hair dryers. Conveniences include safes and desks, as well as phones with free local calls.
Restaurant and Cafe
Grab a bite from the snack bar/deli serving guests of Hampton Inn Cape Girardeau I 55 East. A complimentary buffet breakfast is served daily from 6 AM to 10 AM.
Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape Girardeau Location
With a stay at Fairfield Inn & Suites by Marriott Cape Girardeau in Cape Girardeau, you'll be within a 10-minute drive of Shawnee National Forest and Mississippi River. This hotel is 1.2 mi (1.9 km) from Saint Francis Medical Center and 2.8 mi (4.5 km) from Southeast Missouri Hospital.
Fairfield Inn & Suites by Marriott Cape Girardeau Facility and Service
Don't miss out on recreational opportunities including an indoor pool and a 24-hour fitness center.
Fairfield Inn & Suites by Marriott Cape Girardeau Rooms
Make yourself at home in one of the 103 air-conditioned rooms featuring kitchenettes. Wired and wireless internet access is complimentary, while 55-inch flat-screen televisions with satellite programming provide entertainment. Conveniences include desks and microwaves, as well as phones with free local calls.
Restaurant and Cafe
A complimentary continental breakfast is served daily.
See detailsWith a stay at Fairfield Inn & Suites by Marriott Cape Girardeau in Cape Girardeau, you'll be within a 10-minute drive of Shawnee National Forest and Mississippi River. This hotel is 1.2 mi (1.9 km) from Saint Francis Medical Center and 2.8 mi (4.5 km) from Southeast Missouri Hospital.
Fairfield Inn & Suites by Marriott Cape Girardeau Facility and Service
Don't miss out on recreational opportunities including an indoor pool and a 24-hour fitness center.
Fairfield Inn & Suites by Marriott Cape Girardeau Rooms
Make yourself at home in one of the 103 air-conditioned rooms featuring kitchenettes. Wired and wireless internet access is complimentary, while 55-inch flat-screen televisions with satellite programming provide entertainment. Conveniences include desks and microwaves, as well as phones with free local calls.
Restaurant and Cafe
A complimentary continental breakfast is served daily.
Courtyard By Marriott Cape Girardeau Downtown
Experience the character of a thoughtfully restored property at our hotel in downtown Cape Girardeau, where historic charm blends seamlessly with modern comfort. Our Cape Girardeau, MO hotel places you steps from local restaurants, unique bars, and cultural destinations, along with convenient access to the Southeast Missouri State University campus. You can start or end your day at The Bistro, offering balanced breakfast and dinner options alongside a full bar featuring a curated bourbon selection. After exploring the neighborhood, retreat to well‑designed guest rooms and suites with plush bedding and city views that create a relaxing space to unwind. A spacious 24‑hour fitness center helps you stay on track with your routine. Our family friendly hotel in downtown Cape Girardeau, will be loved by adults and children of all ages. The property also provides versatile event space ideal for small to mid‑sized meetings. Your stay at Courtyard Cape Girardeau Downtown is crafted for comfort and ease.
See detailsAuburn Place Hotel & Suites Cape Girardeau
Rockwood Inn
Property Location
With a stay at Rockwood Inn in Cape Girardeau, you'll be within a 5-minute drive of Shawnee National Forest and Mississippi River. This hotel is 0.2 mi (0.4 km) from Southeast Missouri State University and 0.7 mi (1.2 km) from Show Me Center.
Area Attraction
Distances are displayed to the nearest 0.1 mile and kilometer.
Southeast Missouri State University - 0.4 km / 0.2 mi
Show Me Center - 1.1 km / 0.7 mi
Southeast Missouri Hospital - 1.3 km / 0.8 mi
Century Casino & Hotel Cape Girardeau - 1.7 km / 1.1 mi
EDen Spa & Salon - 2.5 km / 1.6 mi
The Glenn House - 2.7 km / 1.7 mi
Riverfront Bridge Park - 2.8 km / 1.8 mi
Riverfront Park - 3 km / 1.9 mi
Fort D Historic Site - 3.1 km / 1.9 mi
Mississippi River - 3.2 km / 2 mi
Shawnee National Forest - 3.3 km / 2 mi
Cape Rock Park - 4.7 km / 2.9 mi
Cape Splash Family Aquatic Center - 4.7 km / 2.9 mi
Saint Francis Healthcare System - 5.2 km / 3.2 mi
Saint Francis Medical Center - 5.4 km / 3.4 mi
The nearest airports are:
Cape Girardeau, MO (CGI-Cape Girardeau Municipal) - 11.9 km / 7.4 mi
Cairo, IL (CIR-Cairo Regional) - 47.8 km / 29.7 mi
Rec, Spa, Premium Amenities
Take in the views from a garden and make use of amenities such as complimentary wireless internet access and a picnic area.
Business, Other Amenities
Free self parking is available onsite.
Pear Tree Inn Cape Girardeau Near The Medical Cen
“Worth it”
Ideally located in the prime touristic area of Cape Girardeau, Pear Tree Inn Cape Girardeau Near the Medical Cent promises a relaxing and wonderful visit. Featuring a complete list of amenities, guests will find their stay at the property a comfortable one. Free Wi-Fi in all rooms, 24-hour front desk, facilities for disabled guests, luggage storage, Wi-Fi in public areas are just some of the facilities on offer. Comfortable guestrooms ensure a good night's sleep with some rooms featuring facilities such as television LCD/plasma screen, internet access – wireless, internet access – wireless (complimentary), air conditioning, heating. The hotel offers various recreational opportunities. For reliable service and professional staff, Pear Tree Inn Cape Girardeau Near the Medical Cent caters to your needs.
See detailsQuality Inn Cape Girardeau
The well-being of guests is top of mind at Choice-branded hotels. Guests may experience a variety of new, improved cleanliness protocols and products. Get more for your money at the Quality Inn and Suites hotel in Vacaville, CA. Our convenient location near I-80, between Sacramento and San Francisco, makes this hotel your ideal lodging destination when traveling for business or pleasure. For your convenience, our business center offers access to copy and fax services. Guest laundry facilities are available, too. We also have ample parking for buses and trucks. Additional must-have amenities include free WiFi, grab and go breakfast, outdoor pool and a spa. We invite you to relax in your guest room, which features a refrigerator, microwave, coffee maker, hair dryer, iron and ironing board.
See detailsHampton Inn Cape Girardeau I-55 East
incredible service at our Cape Girardeau, MO hotel. From our daily free hot breakfast to our nightly cookie hour, Hampton Inn Cape Girardeau I-55 East makes you feel at home. Located on the southeast corner of I-55 and William Street, our hotel complex includes various shopping and dining options. Walk to seven restaurants within the complex such as Cracker Barrel, Texas Roadhouse and Panera Bread. This beautiful new hotel offers all the amenities you need while traveling. Start your day with a quick workout in the fitness room or with some laps in the heated indoor pool. Sit down to a free, hot breakfast served daily with items including fresh baked waffles, eggs, biscuits and gravy and rotating options. If you’re pressed for time, grab Hampton’s On the Run™ Breakfast Bags, available Monday through Friday. Stay connected to the office with free WiFi in every room or work in the business center with two computer terminals and printing capabilities. End your day at our nightly cookie hour with warm cookies, cold milk and friendly team members available for your questions or concerns. Rest comfortably on a clean and fresh Hampton bed® watching the 37-inch HDTV or with your laptop on the provided lap desk.
See detailsFAQ about Hotels in Cape Girardeau
Hotels in Cape Girardeau
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2. Select a roomOn the hotel detail page, you will see the available room options. Select a room that suits your needs.
3. Complete the booking detailsInput the contact details (the person who will be contacted by tiket.com and the hotel about the booking) and the guests’ details.
4. Select Add-onsYou can also buy additional services such as meal packages, transportation, and many more.
5. Pay your bookingSelect the payment method and complete your transaction. Don’t forget to use the promo code to get a cheaper hotel price at tiket.com.
6. Get the reservation e-voucherAfter the payment is successful, the e-voucher will be available on the Your Orders menu and sent to the email listed in the contact details.