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Exterior & Views 1, Drury Plaza Hotel Cape Girardeau Conference Center, Cape Girardeau
Public Area 2, Drury Plaza Hotel Cape Girardeau Conference Center, Cape Girardeau
Bedroom 3, Drury Plaza Hotel Cape Girardeau Conference Center, Cape Girardeau
Bathroom 4, Drury Plaza Hotel Cape Girardeau Conference Center, Cape Girardeau
Food & Drinks 5, Drury Plaza Hotel Cape Girardeau Conference Center, Cape Girardeau
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Hotel

Drury Plaza Hotel Cape Girardeau Conference Center

Cape Girardeau, Missouri

The Fun Awaits

Suitable for your business trip
Suitable for your business tripStay productive with business facilities.

Reviews

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4.7/5
FantasticFrom 101 reviews
5.0/57 Jul 2026
Jack • Couple Trip
We really enjoy staying here. It's clean, beds are comfortable. Breakfast is very goods and lots of choices.
5.0/57 Jul 2026
Marilyn • Family Trip
Drury Hotels are great. Love the amenities, service, and nice rooms.
5.0/56 Jul 2026
Nelia • Couple Trip
Nice
5.0/56 Jul 2026
Kaitlyn • Couple Trip
I never leave reviews but this place and staff was amazing. I had a bridal shower to attend to on the Sunday at noon and got the hotel for 3 days and 2 nights. We ended up checking out after the first night way later in the afternoon and was only charged for one day. Not sure if they do that for everyone but amazing service. Will return.
5.0/55 Jul 2026
Larry • Couple Trip
Wonderful staff! Room was very comfortable, especially the bed! Enjoyed the food as well.
5.0/54 Jul 2026
Frank • Family Trip
A very pleasant experience after a long days drive.
5.0/53 Jul 2026
crystal • Family Trip
We loved it and will look for this Brand again! It was safe and clean and perfect for an overnight stay.
5.0/51 Jul 2026
Scott
Just a wonderful relaxing place to stay! Terrace on the 8th floor is a nice place to relax in the evening or with coffee in the morning!
5.0/529 Jun 2026
John
Excellent. Great place to stay
5.0/528 Jun 2026
Cheryl
It was absolutely amazing
5.0/528 Jun 2026
Dustin • Family Trip
Right off the hwy very nice
5.0/528 Jun 2026
Nicki • Solo Trip
Other than my coffee pot in my suite. I had the best time. The front desk was able to accommodate my mishap. It was fixed immediately. So quiet, with the cleanest environment. The pool chemicals were exact. Thank you for the great work. Completely satisfied.
5.0/525 Jun 2026
Jeffrey • Solo Trip
Great room and wonderful staff
5.0/524 Jun 2026
Katrina • Family Trip
Excellent hotel clean, breakfast was awesome indoor pool awesome…. Excellent choice for hotel stay.
5.0/523 Jun 2026
Lana • Family Trip
Clean room and great location!!
5.0/523 Jun 2026
John • Family Trip
Would stay here again, no complaints
5.0/521 Jun 2026
Brandon • Trip with Friends
Had a great time staying at the Drury Plaza, all my future stays will be at this location, when I come back into town
5.0/521 Jun 2026
Leah • Solo Trip
The room was clean, the bed was comfortable and I was so impressed with the helpful staff. So nice to have a dinner and breakfast included with the room. Highly recommend this hotel!
5.0/521 Jun 2026
Kellie • Family Trip
Clean spacious king suite, friendly staff, restaurant on site, spacious breakfast area
5.0/519 Jun 2026
Nichole • Family Trip
Perfect

Location

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3351 Percy Drive, Cape Girardeau, Missouri, US
All distances are measured in straight lines. The actual travel distance may be different.

Accommodation Rules

Announcement

- Pets including dogs and cats are accepted at the property. State guidelines for service animals apply, but service animals are free of charge at the property and are welcome in any area frequented by their owners.

- Rooms with pets will be charged a daily pet fee of USD 50 plus tax per night at the property. The property allows up to two pets per room, with a total combined weight of the pets not to exceed 80 pounds.

- Pets are not allowed in any of the public areas of the hotel: dining area, lobby, pool and spa, fitness center, meeting rooms, etc.

- Pets should be leashed or in a pet carrier when traveling to and from guest room (when possible, please use stairwells instead of elevators), and they should not be left alone at any time.

- Housekeeping services will not be provided if pets are left unattended in guest room, and guests will be responsible for any damages or noise complaints pets may cause.

- At check-in, guests traveling with pets will be asked to read and sign the "Pet Guidelines". Pet waste bags are provided to clean up after pets outside.


All rooms are 100% smoke free. Smoking or vaping will result in a USD 250 cleaning fee.
Guests must provide a valid credit card upon check-in to secure any damages incurred during the stay. Pre-preauthorization of USD 50 will be made upon check-in.
Pets are allowed for an additional charge of USD 50 plus tax per night.
Breakfast is served from 06:00 AM to 09:00 AM on weekdays and 07:00 AM to 10:00 AM on weekends.
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Check-in Procedure
Check-in3:00 PM
Check-out11:00

  • Extra-person charges may apply and vary depending on property policy
  • Government-issued photo identification and a credit card may be required at check-in for incidental charges
  • Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
  • This property accepts credit cards and debit cards; cash is not accepted
  • This property reserves the right to pre-authorize the guest's credit card prior to arrival.

Front desk staff will greet guests on arrival at the property. For any questions, please contact the property using the information on the booking confirmation. Information provided by the property may be translated using automated translation tools.

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Want to check in early? Fill out the Special Requests form on the booking page.

More Policies
  • Up to 3 children 18 years old and younger stay free when occupying the parent or guardian's room, using existing bedding.
  • The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation.
  • Guests can arrange to bring pets by contacting the property directly, using the contact information on the booking confirmation (surcharges apply and can be found in the Fees section).
  • Contactless check-in and contactless check-out are available.
  • This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

About Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center Location
When you stay at Drury Plaza Hotel Cape Girardeau Conference Center in Cape Girardeau, you'll be connected to the convention center, within a 10-minute drive of Shawnee National Forest and Mississippi River. This hotel is 0.7 mi (1.1 km) from Saint Francis Medical Center and 2.2 mi (3.5 km) from Saint Francis Healthcare System.

Drury Plaza Hotel Cape Girardeau Conference Center Facility and Service
Be sure to enjoy recreational amenities, including an indoor pool, a hot tub, and a fitness center. This hotel also features complimentary wireless internet access and a banquet hall.

Drury Plaza Hotel Cape Girardeau Conference Center Rooms
Make yourself at home in one of the 168 guestrooms featuring refrigerators and microwaves. 43-inch LCD televisions with cable programming provide entertainment, while complimentary wireless internet access keeps you connected. Bathrooms have shower/tub combinations and hair dryers. Conveniences include desks and separate sitting areas, as well as phones with free local calls.

Restaurant and Cafe
Enjoy a satisfying meal at The Southerner serving guests of Drury Plaza Hotel Cape Girardeau Conference Center. Mingle with other guests at the complimentary reception, held daily. A complimentary buffet breakfast is served on weekdays from 6:00 AM to 9:00 AM and on weekends from 7:00 AM to 10:00 AM.

Room Type and Price

Sun, 11 Oct 2026 - Mon, 12 Oct 2026 (1 night)
1 Room, 1 Adult, 0 Children