
Drury Inn & Suites Cape Girardeau
With a stay at Drury Inn & Suites Cape Girardeau, you'll be centrally located in Cape Girardeau, within a 10-minute drive of Shawnee National Forest and Mississippi River. This hotel is 1.2 mi (2 km) from Saint Francis Medical Center and 2.7 mi (4.3 km) from Saint Francis Healthcare System.
Drury Inn & Suites Cape Girardeau Facility and Service
Be sure to enjoy recreational amenities, including an indoor pool, a hot tub, and a fitness center. Additional features at this hotel include complimentary wireless internet access, a television in a common area, and a banquet hall.
Drury Inn & Suites Cape Girardeau Rooms
Make yourself at home in one of the 87 guestrooms featuring refrigerators and LCD televisions. Complimentary wireless internet access keeps you connected, and cable programming is available for your entertainment. Private bathrooms with shower/tub combinations feature complimentary toiletries and hair dryers. Conveniences include desks and separate sitting areas, as well as phones with free local calls.
Restaurant and Cafe
Meet other guests and eat at the complimentary reception. A complimentary buffet breakfast is served on weekdays from 6:00 AM to 9:00 AM and on weekends from 7:00 AM to 10:00 AM.
Important Information
The following facilities or services will be unavailable from August 10 2026 to August 21 2026 (dates subject to change):
- Hot tub
- Swimming pool

Courtyard By Marriott Cape Girardeau Downtown

Holiday Inn Express & Suites CAPE GIRARDEAU I-55 by IHG

Hampton Inn Cape Girardeau I 55 East
With a stay at Hampton Inn Cape Girardeau I 55 East in Cape Girardeau, you'll be within a 10-minute drive of Shawnee National Forest and Mississippi River. This hotel is 0.5 mi (0.8 km) from Saint Francis Medical Center and 2.3 mi (3.7 km) from Saint Francis Healthcare System.
Hampton Inn Cape Girardeau I 55 East Facility and Service
Don't miss out on recreational opportunities including an indoor pool and a fitness center. Additional features at this hotel include complimentary wireless internet access, a picnic area, and a banquet hall.
Hampton Inn Cape Girardeau I 55 East Rooms
Make yourself at home in one of the 86 guestrooms featuring refrigerators and flat-screen televisions. Complimentary wired and wireless internet access keeps you connected, and cable programming provides entertainment. Private bathrooms with shower/tub combinations feature complimentary toiletries and hair dryers. Conveniences include safes and desks, as well as phones with free local calls.
Restaurant and Cafe
Grab a bite from the snack bar/deli serving guests of Hampton Inn Cape Girardeau I 55 East. A complimentary buffet breakfast is served daily from 6 AM to 10 AM.

Hampton Inn Cape Girardeau I-55 East

Pear Tree Inn Cape Girardeau Near The Medical Cen

Courtyard by Marriott Cape Girardeau Downtown
Located in Cape Girardeau, Courtyard by Marriott Cape Girardeau Downtown is within a 15-minute walk of Southeast Missouri State University and eDen Spa & Salon. This hotel is 0.5 mi (0.7 km) from Shawnee National Forest and 0.6 mi (1 km) from Century Casino & Hotel Cape Girardeau.
Courtyard by Marriott Cape Girardeau Downtown Facility and Service
Take advantage of recreation opportunities such as a 24-hour fitness center or take in the view from a terrace and a garden. This hotel also features complimentary wireless internet access and gift shops/newsstands.
Courtyard by Marriott Cape Girardeau Downtown Rooms
Make yourself at home in one of the 91 guestrooms featuring refrigerators. Your bed comes with down comforters and Egyptian cotton sheets. Complimentary wired and wireless internet access keeps you connected, and satellite programming provides entertainment. Private bathrooms with bathtubs or showers feature complimentary toiletries and hair dryers.
Restaurant and Cafe
Satisfy your appetite with American cuisine at The Bistro, a bistro which features a bar/lounge. Dining is also available at the coffee shop/cafe. Cooked-to-order breakfasts are served on weekdays from 6:30 AM to 9:30 AM and on weekends from 7:00 AM to 10:00 AM for a fee.

Candlewood Suites CAPE GIRARDEAU
A historic college town in southeastern Missouri, Cape Girardeau is bordered on the east by the mighty Mississippi River. The only extended stay in the area, the Candlewood Suites® Cape Girardeau hotel's spacious suites offer travelers a room to work and a place to relax, as well as convenient access to the best attractions in Cape Girardeau, MO.
The newly renovated hotel's location is just off I-55 in southeastern Missouri, convenient to St. Francis Hospital and Landmark Hospital. Convenient to the regional airport. Business travelers appreciate such amenities as free high-speed, wireless Internet access and a 24-hour Business Center with printing capabilities.
Cape Girardeau location is also exciting for leisure travelers. Nearby Southeast Missouri State University provides year-round opportunities for sporting events and cultural activities. Nature lovers enjoy the area's beautiful vistas and numerous parks, including the Trail of Tears State Park. The Shawnee Park Sports Complex is also near this hotel's Cape Girardeau location.
Guests can expect convenient amenities at this hotel, including a free guest laundry facility and a 24-hour Fitness Center. The outdoor Gazebo Grill area is the perfect place to gather with friends and family, and the indoor pool is the perfect place to cool off after a long day. Visit historic Cape Girardeau, MO and meet the hotel's friendly staff.

Auburn Place Hotel & Suites Cape Girardeau

Drury Plaza Hotel Cape Girardeau Conference Center
When you stay at Drury Plaza Hotel Cape Girardeau Conference Center in Cape Girardeau, you'll be connected to the convention center, within a 10-minute drive of Shawnee National Forest and Mississippi River. This hotel is 0.7 mi (1.1 km) from Saint Francis Medical Center and 2.2 mi (3.5 km) from Saint Francis Healthcare System.
Drury Plaza Hotel Cape Girardeau Conference Center Facility and Service
Be sure to enjoy recreational amenities, including an indoor pool, a hot tub, and a fitness center. This hotel also features complimentary wireless internet access and a banquet hall.
Drury Plaza Hotel Cape Girardeau Conference Center Rooms
Make yourself at home in one of the 168 guestrooms featuring refrigerators and microwaves. 43-inch LCD televisions with cable programming provide entertainment, while complimentary wireless internet access keeps you connected. Bathrooms have shower/tub combinations and hair dryers. Conveniences include desks and separate sitting areas, as well as phones with free local calls.
Restaurant and Cafe
Enjoy a satisfying meal at The Southerner serving guests of Drury Plaza Hotel Cape Girardeau Conference Center. Mingle with other guests at the complimentary reception, held daily. A complimentary buffet breakfast is served on weekdays from 6:00 AM to 9:00 AM and on weekends from 7:00 AM to 10:00 AM.

Pear Tree Inn Cape Girardeau West
Located in Cape Girardeau, Pear Tree Inn Cape Girardeau West is in a rural location, a 3-minute drive from Saint Francis Medical Center and 5 minutes from Saint Francis Healthcare System. This hotel is 4.5 mi (7.2 km) from Shawnee National Forest and 4.8 mi (7.8 km) from Mississippi River.
Pear Tree Inn Cape Girardeau West Facility and Service
Make use of convenient amenities, which include complimentary wireless internet access and a television in a common area.
Pear Tree Inn Cape Girardeau West Rooms
Make yourself at home in one of the 81 guestrooms featuring refrigerators and LCD televisions. Complimentary wireless internet access is available to keep you connected. Bathrooms have shower/tub combinations and hair dryers. Conveniences include desks and microwaves, as well as phones with free local calls.
Restaurant and Cafe
A complimentary buffet breakfast is served on weekdays from 6:00 AM to 9:00 AM.

Fairfield Inn & Suites by Marriott Cape Girardeau
With a stay at Fairfield Inn & Suites by Marriott Cape Girardeau in Cape Girardeau, you'll be within a 10-minute drive of Shawnee National Forest and Mississippi River. This hotel is 1.2 mi (1.9 km) from Saint Francis Medical Center and 2.8 mi (4.5 km) from Southeast Missouri Hospital.
Fairfield Inn & Suites by Marriott Cape Girardeau Facility and Service
Don't miss out on recreational opportunities including an indoor pool and a 24-hour fitness center.
Fairfield Inn & Suites by Marriott Cape Girardeau Rooms
Make yourself at home in one of the 103 air-conditioned rooms featuring kitchenettes. Wired and wireless internet access is complimentary, while 55-inch flat-screen televisions with satellite programming provide entertainment. Conveniences include desks and microwaves, as well as phones with free local calls.
Restaurant and Cafe
A complimentary continental breakfast is served daily.
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